Methyl 10,12-pentacosadiynoate

Base Information

• Chemical Name: Methyl 10,12-pentacosadiynoate
• CAS No.: 120650-77-3
• Molecular Formula: C26H44O2
• Molecular Weight: 388.63
• Mol file: 120650-77-3.mol

Synonyms:Methyl 10,12-pentacosadiynoate;10,12-Pentacosadiynoic Acid Methyl Ester;

Chemical Property of Methyl 10,12-pentacosadiynoate

Chemical Property:

• Vapor Pressure: 8.39E-10mmHg at 25°C
• Melting Point: 27-28oC
• Boiling Point: 491.4°C at 760 mmHg
• Flash Point: 208°C
• PSA: 26.30000
• Density: 0.908g/cm³
• LogP: 7.59800
• Sensitive.: Light Sensitive

Purity/Quality:

98%min ^*data from raw suppliers

10,12-Pentacosadiynoic Acid Methyl Ester ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 10,12-Pentacosadiynoic Acid Methyl Ester is a reactant in the preparation of Diacetylenic hydroxamic acids.

Technology Process of Methyl 10,12-pentacosadiynoate

There total 3 articles about Methyl 10,12-pentacosadiynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methanol (67-56-1) + 10,12-pentacosanodiynoic acid (66990-32-7) → methyl pentacosa-10,12-diynoate (120650-77-3)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/acs.macromol.5b02683

Reference yield:

10,12-pentacosanodiynoic acid (66990-32-7) → methyl pentacosa-10,12-diynoate (120650-77-3)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅ / benzene / Heating

2: 50 °C

With phosphorus pentachloride; In benzene;

DOI:10.1007/BF00766548

Reference yield:

methanol (67-56-1) + pentacosa-10,12-diynoyl chloride (128937-83-7) → methyl pentacosa-10,12-diynoate (120650-77-3)

Guidance literature:

at 50 ℃;

DOI:10.1007/BF00766548

upstream raw materials:

methanol

pentacosa-10,12-diynoyl chloride

10,12-pentacosanodiynoic acid