2-Hydroxy-3-methoxybenzamide

Base Information

Chemical Name:2-Hydroxy-3-methoxybenzamide
CAS No.:26751-04-2
Molecular Formula:C8H9NO3
Molecular Weight:167.164
Hs Code.:2924299090
DSSTox Substance ID:DTXSID20368856
Nikkaji Number:J3.074.799B
Wikidata:Q82155713
Mol file:26751-04-2.mol

Synonyms:2-hydroxy-3-methoxybenzamide;26751-04-2;2-hydroxy-3-methoxy-benzamide;SCHEMBL1355519;DTXSID20368856;HMS1719L13;BBA75104;AKOS000207603;MB03777;BS-27786;CS-0450537;EN300-11066;E86857;J-509616;Z57032585

Suppliers and Price of 2-Hydroxy-3-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-3-methoxybenzamide
1g
$ 400.00

Crysdot
2-Hydroxy-3-methoxybenzamide 97%
5g
$ 847.00

American Custom Chemicals Corporation
2-HYDROXY-3-METHOXYBENZAMIDE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
2-HYDROXY-3-METHOXYBENZAMIDE 95.00%
1G
$ 852.55

American Custom Chemicals Corporation
2-HYDROXY-3-METHOXYBENZAMIDE 95.00%
5G
$ 1548.26

Alichem
2-Hydroxy-3-methoxybenzamide
1g
$ 1460.20

Alichem
2-Hydroxy-3-methoxybenzamide
500mg
$ 798.70

Alichem
2-Hydroxy-3-methoxybenzamide
250mg
$ 480.00

AK Scientific
2-Hydroxy-3-methoxybenzamide
10g
$ 2002.00

AK Scientific
2-Hydroxy-3-methoxybenzamide
500mg
$ 409.00

Total 3 raw suppliers

Chemical Property of 2-Hydroxy-3-methoxybenzamide

Chemical Property:

Vapor Pressure:0.00108mmHg at 25°C
Boiling Point:291.9°Cat760mmHg
Flash Point:130.3°C
PSA：73.54000
Density:1.28g/cm³
LogP:1.38390
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:167.058243149
Heavy Atom Count:12
Complexity:172

Purity/Quality:

99% ^*data from raw suppliers

2-Hydroxy-3-methoxybenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1O)C(=O)N
Uses 2-Hydroxy-3-methoxybenzamide is used in preparation of Benzamide, Benzoxazinone, Benzothiazinone and Quinazolinone derivatives useful for preventing or treating diseases associated with poly(ADP-ribose) polymerase-1.

Technology Process of 2-Hydroxy-3-methoxybenzamide

There total 3 articles about 2-Hydroxy-3-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 6342-70-7
3-methoxymethylsalicylate

: 26751-04-2
2-hydroxy-3-methoxybenzamide

Guidance literature:: With ammonia; In methanol; at 80 ℃; for 16h; Sealed tube;

Reference yield: 71.0%

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 26751-04-2
2-hydroxy-3-methoxybenzamide

Guidance literature:: With hydroxylamine hydrochloride; caesium carbonate; In acetonitrile; at 60 - 65 ℃;
DOI:10.1016/j.tetlet.2012.03.051

Reference yield:

: 877-22-5
3-methoxysalicylic acid

: 26751-04-2
2-hydroxy-3-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 16 h / Reflux

2: ammonia / methanol / 16 h / 80 °C / Sealed tube

With sulfuric acid; ammonia; In methanol;