2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-

Base Information

Chemical Name:2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-
CAS No.:182950-96-5
Molecular Formula:C13H14O3
Molecular Weight:218.252
Hs Code.:
DSSTox Substance ID:DTXSID80464742
Nikkaji Number:J2.388.983H
Wikidata:Q82290203

Synonyms:2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-;182950-96-5;SCHEMBL7080429;DTXSID80464742

Suppliers and Price of 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:218.094294304
Heavy Atom Count:16
Complexity:266

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC(=O)CC1=O)CCC2=CC=CC=C2
Isomeric SMILES:C1[C@@H](OC(=O)CC1=O)CCC2=CC=CC=C2

Technology Process of 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-

There total 16 articles about 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 862464-32-2
methyl (5S)-5-hydroxy-3-oxo-7-phenylheptanoate

: 182950-96-5
(6S)-6-(2-phenylethyl)dihydropyran-2,4⁽³⁾-dione

Guidance literature:: With sodium carbonate; In methanol; for 12h;
DOI:10.1134/S1070428013050138

Reference yield: 79.0%

: 182950-95-4
(S)-5-hydroxy-3-oxo-7-phenyl-heptanoic acid tert-butyl ester

: 182950-96-5
(6S)-6-(2-phenylethyl)dihydropyran-2,4⁽³⁾-dione

Guidance literature:: With trifluoroacetic acid; In dichloromethane;
DOI:10.1016/0040-4039(96)01429-3

Reference yield:

: 30414-58-5
methyl 3-oxo-5-phenylpentanoate

: 182950-96-5
(6S)-6-(2-phenylethyl)dihydropyran-2,4⁽³⁾-dione

Guidance literature:: Multi-step reaction with 5 steps

1.1: 80 percent / sodium borohydride / methanol / 0 - 20 °C

2.1: 46 percent / lipase PS-C / diisopropyl ether / 18 h

3.1: 90 percent / potassium carbonate / methanol

4.1: lithium diisopropylamide / tetrahydrofuran / -78 °C

4.2: tetrahydrofuran / -78 °C

5.1: TFA / CH₂Cl₂ / 10 h

With sodium tetrahydroborate; potassium carbonate; trifluoroacetic acid; lithium diisopropyl amide; Lipase PS-C; In tetrahydrofuran; methanol; dichloromethane; di-isopropyl ether;
DOI:10.1016/j.tetlet.2006.09.155