Silane, (1,1-dimethylethyl)dimethyl[[(1S)-1-phenyl-3-butenyl]oxy]-

Base Information

• Chemical Name: Silane, (1,1-dimethylethyl)dimethyl[[(1S)-1-phenyl-3-butenyl]oxy]-
• CAS No.: 183620-66-8
• Molecular Formula: C16H26OSi
• Molecular Weight: 262.467
• DSSTox Substance ID: DTXSID30472473
• Nikkaji Number: J2.370.246K
• Wikidata: Q82301437
• Mol file: 183620-66-8.mol

Synonyms:Silane, (1,1-dimethylethyl)dimethyl[[(1S)-1-phenyl-3-butenyl]oxy]-;183620-66-8;DTXSID30472473

Chemical Property of Silane, (1,1-dimethylethyl)dimethyl[[(1S)-1-phenyl-3-butenyl]oxy]-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 262.175291983
• Heavy Atom Count: 18
• Complexity: 259

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OC(CC=C)C1=CC=CC=C1
• Isomeric SMILES: CC(C)(C)[Si](C)(C)O[C@@H](CC=C)C1=CC=CC=C1

Technology Process of Silane, (1,1-dimethylethyl)dimethyl[[(1S)-1-phenyl-3-butenyl]oxy]-

There total 5 articles about Silane, (1,1-dimethylethyl)dimethyl[[(1S)-1-phenyl-3-butenyl]oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

(S)-1-Phenyl-3-buten-1-ol (77118-87-7,936-58-3) + tert-butyldimethylsilyl chloride (18162-48-6) → tert-butyl-dimethyl-(1-phenyl-but-3-enyloxy)-silane (183620-66-8)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 0 - 22 ℃; for 16h; Inert atmosphere;

DOI:10.1039/c6dt04612f

Reference yield:

t-butyldimethylsiyl triflate (69739-34-0) + (S)-1-Phenyl-3-buten-1-ol (77118-87-7,936-58-3) → tert-butyl-dimethyl-(1-phenyl-but-3-enyloxy)-silane (183620-66-8)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 0 ℃; for 0.25h;

DOI:10.1039/CC9960002229

Reference yield:

benzaldehyde (100-52-7) → tert-butyl-dimethyl-(1-phenyl-but-3-enyloxy)-silane (183620-66-8)

Guidance literature:

Multi-step reaction with 2 steps

2: 2,6-lutidine / CH₂Cl₂ / 0.25 h / 0 °C

With 2,6-dimethylpyridine; In dichloromethane;

DOI:10.1039/CC9960002229

upstream raw materials:

t-butyldimethylsiyl triflate

(S)-1-Phenyl-3-buten-1-ol

tert-butyldimethylsilyl chloride

benzaldehyde

Downstream raw materials:

(S)-3-((tert-butyldimethylsilyl)oxy)-3-phenylpropanal

(S)-1-Phenyl-3-buten-1-ol

(-)-(S)-5-phenyl-4,5-dihydrofuran-2(3H)-one