1-(TRIMETHYLSILYL)-4-TERT-BUTYLBENZENE

Base Information

• Chemical Name: 1-(TRIMETHYLSILYL)-4-TERT-BUTYLBENZENE
• CAS No.: 18412-68-5
• Molecular Formula: C13H22Si
• Molecular Weight: 206.403
• Mol file: 18412-68-5.mol

Synonyms:4-trimethylsilyl-1-t-butylbenzene;(4-tert-Butyl-phenyl)-trimethyl-silan;4-tert-butylphenyltrimethylsilane;Trimethyl-(4-tert.-butyl-phenyl)-silan;(4-tert-butyl-phenyl)-trimethyl-silane;1-trimethylsilyl-4-tert-butylbenzene;

Chemical Property of 1-(TRIMETHYLSILYL)-4-TERT-BUTYLBENZENE

Chemical Property:

• PSA: 0.00000
• LogP: 3.52930

Purity/Quality:

99% ^*data from raw suppliers

1-(TRIMETHYLSILYL)-4-tert-BUTYLBENZENE ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(TRIMETHYLSILYL)-4-TERT-BUTYLBENZENE

There total 8 articles about 1-(TRIMETHYLSILYL)-4-TERT-BUTYLBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

chloro-trimethyl-silane (75-77-4) + 1-bromo-4-tert-butylbenzene (3972-65-4) → (4-tert-butylphenyl)trimethylsilane (18412-68-5)

Guidance literature:

1-bromo-4-tert-butylbenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at -78 - 20 ℃;

DOI:10.1021/ja408712e

Reference yield: 90.0%

chloro-trimethyl-silane (75-77-4) + 4-(tert-butyl)chlorobenzene (3972-56-3) → (4-tert-butylphenyl)trimethylsilane (18412-68-5)

Guidance literature:

With magnesium; sodium iodide; In tetrahydrofuran; at 25 ℃; for 10h; Glovebox; Inert atmosphere;

Reference yield: 87.0%

chloro-trimethyl-silane (75-77-4) + 1-(4-tert-butylphenyl)-2,5-diphenyl-1H-pyrrole → (4-tert-butylphenyl)trimethylsilane (18412-68-5) + C19H21NSi

Guidance literature:

1-(4-tert-butylphenyl)-2,5-diphenyl-1H-pyrrole; With lithium; In tetrahydrofuran; at 0 ℃; for 8h; Schlenk technique; Inert atmosphere;

chloro-trimethyl-silane; In tetrahydrofuran; at 0 ℃; for 2h; Reagent/catalyst; Schlenk technique; Inert atmosphere;

DOI:10.1055/a-1482-2567

upstream raw materials:

chloro-trimethyl-silane

4-tert-butylmagnesium bromide

1-bromo-4-tert-butylbenzene

4-(tert-butyl)chlorobenzene

Downstream raw materials:

4-tert-butyl-1-(dibromoboryl)benzene

(p-(t)BuC₆H₄)2BBr

1-tert-butyl-4-fluorobenzene

C₃₂H₂₉BN₂O