7-Methoxy-2,3-diphenyl-4H-chromen-4-one

Base Information

Chemical Name:7-Methoxy-2,3-diphenyl-4H-chromen-4-one
CAS No.:18720-69-9
Molecular Formula:C22H16O3
Molecular Weight:328.367
Hs Code.:2914509090
DSSTox Substance ID:DTXSID00348075
Nikkaji Number:J1.402.530H
Wikidata:Q82122596
Mol file:18720-69-9.mol

Synonyms:7-Methoxy-2,3-diphenyl-4H-chromen-4-one;18720-69-9;7-methoxy-2,3-diphenylchromen-4-one;7-Methoxy-3-phenylflavone;Oprea1_846171;DTXSID00348075;7-Methoxy-2,3-diphenyl-chromen-4-one

Suppliers and Price of 7-Methoxy-2,3-diphenyl-4H-chromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 7-Methoxy-2,3-diphenyl-4H-chromen-4-one

Chemical Property:

PSA：39.44000
LogP:5.13560
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:328.109944368
Heavy Atom Count:25
Complexity:511

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=O)C(=C(O2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 7-Methoxy-2,3-diphenyl-4H-chromen-4-one

There total 5 articles about 7-Methoxy-2,3-diphenyl-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

: 33454-09-0
phenyl 2-hydroxy-4-methoxybenzoate

: 501-65-5
diphenyl acetylene

: 18720-69-9
2,3-diphenyl-7-methoxy-4H-1-benzopyran-4-one

Guidance literature:: With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; sodium phenoxide; In dimethyl sulfoxide; at 120 ℃; for 18h; Sealed tube; Glovebox;
DOI:10.1246/cl.200885

Reference yield:

: 74719-07-6
1-<2-(benzoyloxy)-4-methoxyphenyl>-2-phenylethanone

: 18720-69-9
2,3-diphenyl-7-methoxy-4H-1-benzopyran-4-one

Guidance literature:: With sodium hydroxide; Yield given. Multistep reaction; 1.) glycerol, 260 deg C, 2 h, 2.) a) RT, 15 min, b) 0-4 deg C, 24 h;
DOI:10.1021/jm00174a018

Reference yield:

: 18439-96-8
1-(2-hydroxy-4-methoxyphenyl)-2-phenylethanone

: 18720-69-9
2,3-diphenyl-7-methoxy-4H-1-benzopyran-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 500 mg / pyridine / 5 h / Ambient temperature

2: 2.) 4 N NaOH / 1.) glycerol, 260 deg C, 2 h, 2.) a) RT, 15 min, b) 0-4 deg C, 24 h

With pyridine; sodium hydroxide;
DOI:10.1021/jm00174a018