Methyl-phosphonic acid (2R,3R,4S,5R)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester methyl ester

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Chemical Name:Methyl-phosphonic acid (2R,3R,4S,5R)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester methyl ester
CAS No.:115561-48-3
Molecular Formula:C₅₈H₆₀N₅O₁₀P
Molecular Weight:1018.12
Hs Code.:

Methyl-phosphonic acid (2R,3R,4S,5R)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester methyl ester

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Chemical Property of Methyl-phosphonic acid (2R,3R,4S,5R)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester methyl ester

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Technology Process of Methyl-phosphonic acid (2R,3R,4S,5R)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester methyl ester

There total 1 articles about Methyl-phosphonic acid (2R,3R,4S,5R)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 676-83-5
methyldichlorophosphane

: 115561-36-9
N⁶-(4-monomethoxytrityl)-9-<2-O-(4-monomethoxytrityl)-3-O-(methoxytetrahydropyranyl)-β-D-arabinofuranosyl>adenine

: 115590-44-8
C₁₁₃H₁₁₁N₁₀O₁₇P

: 115561-48-3
Methyl-phosphonic acid (2R,3R,4S,5R)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-5-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester methyl ester

Guidance literature:: With sodium tetrahydroborate; mercury(II) diacetate; Yield given. Multistep reaction; 1) reflux, 2) CH₂Cl₂, water, 20 deg C;