4H-1-Benzopyran-4-one, 7-methoxy-2-(methylthio)-3-phenyl-

Base Information

Chemical Name:4H-1-Benzopyran-4-one, 7-methoxy-2-(methylthio)-3-phenyl-
CAS No.:189872-43-3
Molecular Formula:C17H14O3S
Molecular Weight:298.362
Hs Code.:
DSSTox Substance ID:DTXSID20476985
Nikkaji Number:J1.772.098H
Wikidata:Q82308988
Mol file:189872-43-3.mol

Synonyms:4H-1-Benzopyran-4-one, 7-methoxy-2-(methylthio)-3-phenyl-;189872-43-3;DTXSID20476985

Suppliers and Price of 4H-1-Benzopyran-4-one, 7-methoxy-2-(methylthio)-3-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4H-1-Benzopyran-4-one, 7-methoxy-2-(methylthio)-3-phenyl-

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:298.06636548
Heavy Atom Count:21
Complexity:426

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=O)C(=C(O2)SC)C3=CC=CC=C3

Technology Process of 4H-1-Benzopyran-4-one, 7-methoxy-2-(methylthio)-3-phenyl-

There total 4 articles about 4H-1-Benzopyran-4-one, 7-methoxy-2-(methylthio)-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 75-15-0,12122-00-8
carbon disulfide

: 18439-96-8
1-(2-hydroxy-4-methoxyphenyl)-2-phenylethanone

: 74-88-4
methyl iodide

: 189872-43-3
7-methoxy-2-methylthio-3-phenyl-4H-1-benzopyran-4-one

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran; water; at 20 ℃;
DOI:10.1016/S0040-4039(02)01342-4

Reference yield:

: 103-82-2
phenylacetic acid

: 189872-43-3
7-methoxy-2-methylthio-3-phenyl-4H-1-benzopyran-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / BF₃*OEt₂ / 2 h / 100 °C

2: 88 percent / PPh₃; DIAD / tetrahydrofuran / 0.08 h / 20 °C

3: 87 percent / n-Bu₄N*HSO₄; aq. NaOH / tetrahydrofuran; H₂O / 20 °C

With sodium hydroxide; di-isopropyl azodicarboxylate; boron trifluoride diethyl etherate; tetra(n-butyl)ammonium hydrogensulfate; triphenylphosphine; In tetrahydrofuran; water; 1: Friedel-Crafts acylation / 2: Mitsunobu reaction;
DOI:10.1016/S0040-4039(02)01342-4

Reference yield:

: 3669-41-8
1-(2,4-dihydroxyphenyl)-2-phenylethanone

: 189872-43-3
7-methoxy-2-methylthio-3-phenyl-4H-1-benzopyran-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / PPh₃; DIAD / tetrahydrofuran / 0.08 h / 20 °C

2: 87 percent / n-Bu₄N*HSO₄; aq. NaOH / tetrahydrofuran; H₂O / 20 °C

With sodium hydroxide; di-isopropyl azodicarboxylate; tetra(n-butyl)ammonium hydrogensulfate; triphenylphosphine; In tetrahydrofuran; water; 1: Mitsunobu reaction;
DOI:10.1016/S0040-4039(02)01342-4