2-Azabicyclo[2.2.1]heptane-3-carboxylic acid, 2-[(1R)-1-phenylethyl]-, ethyl ester, (1R,3S,4S)-

Base Information

Chemical Name:2-Azabicyclo[2.2.1]heptane-3-carboxylic acid, 2-[(1R)-1-phenylethyl]-, ethyl ester, (1R,3S,4S)-
CAS No.:192461-70-4
Molecular Formula:C17H23NO2
Molecular Weight:273.375
Hs Code.:
Mol file:192461-70-4.mol

Synonyms:(1R,3S,4S)-2-((R)-1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid ethyl ester;(1R,3S,4S)-ethyl 2-((R)-1-phenylethyl)-2-azabicyclo[2.2.1]heptane-3-carboxylate;

Suppliers and Price of 2-Azabicyclo[2.2.1]heptane-3-carboxylic acid, 2-[(1R)-1-phenylethyl]-, ethyl ester, (1R,3S,4S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2-Azabicyclo[2.2.1]heptane-3-carboxylic acid, 2-[(1R)-1-phenylethyl]-, ethyl ester, (1R,3S,4S)-

Chemical Property:

PSA：29.54000
LogP:3.10150

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 2-Azabicyclo[2.2.1]heptane-3-carboxylic acid, 2-[(1R)-1-phenylethyl]-, ethyl ester, (1R,3S,4S)-

There total 6 articles about 2-Azabicyclo[2.2.1]heptane-3-carboxylic acid, 2-[(1R)-1-phenylethyl]-, ethyl ester, (1R,3S,4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 134984-63-7
(1S,3S,4R)-2-((R)-1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid ethyl ester

: 192461-70-4
ethyl (1R,3S,4S)-2-<(R)-1-phenylethyl>-2-azabicyclo<2.2.1>heptane-3-exo-carboxylate

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; under 1551.49 Torr;

Reference yield: 82.0%

: (1S,3S,4R)-ethyl 2-((R)-1-phenylethyl)-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate

: 192461-70-4
ethyl (1R,3S,4S)-2-<(R)-1-phenylethyl>-2-azabicyclo<2.2.1>heptane-3-exo-carboxylate

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In ethanol; at 20 ℃; for 1h;

Reference yield:

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 192461-70-4
ethyl (1R,3S,4S)-2-<(R)-1-phenylethyl>-2-azabicyclo<2.2.1>heptane-3-exo-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium sulfate / toluene / 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

3.1: palladium on activated charcoal; hydrogen / ethanol / 20 °C / 1551.49 Torr

With palladium on activated charcoal; hydrogen; sodium sulfate; trifluoroacetic acid; In ethanol; N,N-dimethyl-formamide; toluene;