N-3-Hydroxydecanoyl-L-hoMoserine Lactone

Base Information

• Chemical Name: N-3-Hydroxydecanoyl-L-hoMoserine Lactone
• CAS No.: 192883-12-8
• Molecular Formula: C14H25NO4
• Molecular Weight: 271.35300
• Mol file: 192883-12-8.mol

Synonyms:

Chemical Property of N-3-Hydroxydecanoyl-L-hoMoserine Lactone

Chemical Property:

• PSA: 75.63000
• LogP: 1.92050

Purity/Quality:

99% ^*data from raw suppliers

N-3-Hydroxydecanoyl-L-homoserineLactone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: N-3-hydroxydecanoyl-L-Homoserine lactone is a bacterial quorum-sensing molecule that has been found in B. pseudomallei. It induces expression of tda, a gene with roles in the production of the antibiotic tropodithietic acid (TDA; ) and the algicide roseobacticide, in P. inhibens.
• Uses: N-3-hydroxydecanoyl-L-homoserine Lactone is a small signaling molecule that is secreted by different types of gram-negative bacteria as a autoinducer. N-3-hydroxydecanoyl-L-homoserine Lactone has been used in studies involving interspecies signaling through QscR, a quorum receptor of pseudomonas aeruginosa.

Technology Process of N-3-Hydroxydecanoyl-L-hoMoserine Lactone

There total 5 articles about N-3-Hydroxydecanoyl-L-hoMoserine Lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxydecanoic acid (5561-87-5,19525-80-5,19526-23-9,33044-91-6,14292-26-3) + α-amino-γ-butyrolactone hydrobromide (6305-38-0) → N-(3-hydroxy-decanoyl)-L-homoserine lactone (192883-12-8,929222-14-0)

Guidance literature:

α-amino-γ-butyrolactone hydrobromide; With N-ethyl-N,N-diisopropylamine; In tert-Amyl alcohol; at 70 ℃; for 0.5h;

3-hydroxydecanoic acid; With sodium sulfate; In tert-Amyl alcohol; at 70 ℃; for 120h; stereospecific reaction;

DOI:10.1007/s10562-017-2261-8

Reference yield:

S-(5’-adenosyl)-L-methionine chloride dihydrochloride (86867-01-8) + (R)-S-(3-hydroxydecanoyl)-N-pantothenoylcysteamine → N-(3-hydroxy-decanoyl)-L-homoserine lactone (192883-12-8,929222-14-0)

Guidance literature:

With Phaeobacter inhibens PgaI₂; In dimethyl sulfoxide; glycerol; at 28 ℃; for 5h; Reagent/catalyst; Enzymatic reaction;

DOI:10.3762/bjoc.14.112

Reference yield:

2,2-dimethyl-5-octanoyl-1,3-dioxane-4,6-dione (103576-44-9) → N-(3-hydroxy-decanoyl)-L-homoserine lactone (192883-12-8,929222-14-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 70 °C

2: sodium cyanoborohydride; hydrogenchloride / methanol / pH 3 - 4

With hydrogenchloride; sodium cyanoborohydride; In methanol; acetonitrile;

DOI:10.1007/s13361-017-1777-x

upstream raw materials:

2,2-dimethyl-5-octanoyl-1,3-dioxane-4,6-dione

N-(3-oxodecanoyl)-L-homoserine lactone

Octanoic acid

3-hydroxydecanoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 192883-12-8 N-3-Hydroxydecanoyl-L-hoMoserine Lactone

Send

Send

Metric Ton KG G Pound L ML

Send

Send