2,4-Dimethyl-1,2,3,4-tetrahydroquinoline

Base Information

• Chemical Name: 2,4-Dimethyl-1,2,3,4-tetrahydroquinoline
• CAS No.: 19343-79-4
• Molecular Formula: C11H15N
• Molecular Weight: 161.247
• European Community (EC) Number: 821-767-5
• DSSTox Substance ID: DTXSID30446730
• Nikkaji Number: J556.592H
• Mol file: 19343-79-4.mol

Synonyms:2,4-dimethyl-1,2,3,4-tetrahydroquinoline;19343-79-4;rac-(2R,4S)-2,4-dimethyl-1,2,3,4-tetrahydroquinoline, cis;Quinoline, 1,2,3,4-tetrahydro-2,4-dimethyl-;SCHEMBL9384154;2,4-dimethyl-tetrahydroquinoline;DTXSID30446730;MFCD18448809;AKOS006373890;DS-12157;CS-0161529;C73677;EN300-1233853;A919575

Chemical Property of 2,4-Dimethyl-1,2,3,4-tetrahydroquinoline

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 161.120449483
• Heavy Atom Count: 12
• Complexity: 155

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC(NC2=CC=CC=C12)C

Technology Process of 2,4-Dimethyl-1,2,3,4-tetrahydroquinoline

There total 3 articles about 2,4-Dimethyl-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

→ 2,4-dimethylquinoline (1198-37-4) + 2,4-dimethyl-1,2,3,4-tetrahydroquinoline (19343-79-4)

Guidance literature:

pentacarbonyl(1-[N-(2-(2-propenyl)phenyl)amino]ethylidene)chromium; In toluene; at 120 ℃; for 16h;

With air; for 24h;

DOI:10.1016/j.tet.2003.09.028

Reference yield:

2-isopropenylaniline (52562-19-3) → 2,4-dimethylquinoline (1198-37-4) + trans-2,4-Dimethyl-1,2,3,4-tetrahydroquinoline (19343-79-4,67525-05-7,67525-06-8) + (2RS,4SR)-2,4-dimethyl-1,2,3,4-tetrahydroquinoline (19343-79-4,67525-05-7,67525-06-8)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1021/jo00073a009

Reference yield:

2-isopropenylaniline (52562-19-3) → 2,4-dimethylquinoline (1198-37-4) + trans-2,4-Dimethyl-1,2,3,4-tetrahydroquinoline (19343-79-4,67525-05-7,67525-06-8) + (2RS,4SR)-2,4-dimethyl-1,2,3,4-tetrahydroquinoline (19343-79-4,67525-05-7,67525-06-8)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1021/jo00073a009

upstream raw materials:

2-isopropenylaniline

Downstream raw materials:

1-benzoyl-2,4-dimethyl-1,2,3,4-tetrahydro-quinoline

2,4-dimethylquinoline

4-methyl-2-phenethylquinoline