4-methyl-2-phenethylquinoline

Base Information

• Chemical Name: 4-methyl-2-phenethylquinoline
• CAS No.: 137634-62-9
• Molecular Formula: C₁₈H₁₇N
• Molecular Weight: 247.34
• Mol file: 137634-62-9.mol

Synonyms:4-methyl-2-phenethylquinoline

Chemical Property of 4-methyl-2-phenethylquinoline

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-methyl-2-phenethylquinoline

There total 14 articles about 4-methyl-2-phenethylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C6H4NCH2CHCCH2 (491-35-0) + 2-Phenylethyl hydrogen oxalate (137634-59-4) → bis(2-phenylethyl) oxalate (99559-02-1) + 4-methyl-2-phenethylquinoline (137634-62-9)

Guidance literature:

With bis-[(trifluoroacetoxy)iodo]benzene; In benzene; Heating;

Reference yield: 75.0%

benzaldehyde (100-52-7) + 2,4-dimethyl-1,2,3,4-tetrahydroquinoline (19343-79-4) → 4-methyl-2-phenethylquinoline (137634-62-9)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; benzoic acid; In para-xylene; at 150 ℃; for 20h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c6cc03996k

Reference yield: 75.0%

C6H4NCH2CHCCH2 (491-35-0) + (2-phenylethyl)boronic acid (34420-17-2) → 4-methyl-2-phenethylquinoline (137634-62-9)

Guidance literature:

With [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; oxygen; trifluoroacetic acid; In dimethyl sulfoxide; at 20 ℃; for 24h; Sealed tube; Irradiation;

DOI:10.1039/d0cc05946c

upstream raw materials:

C₆H₄NCH₂CHCCH₂

2-Phenylethyl hydrogen oxalate

iodobenzene di(3-phenylpropanoate)

3-Phenylpropionic acid