tetrahydro-2H-thiopyran-4-ol 1,1-dioxide(SALTDATA: FREE)

Base Information

• Chemical Name: tetrahydro-2H-thiopyran-4-ol 1,1-dioxide(SALTDATA: FREE)
• CAS No.: 194152-05-1
• Molecular Formula: C5H10O3S
• Molecular Weight: 150.199
• Hs Code.: 2934999090
• Mol file: 194152-05-1.mol

Synonyms:1,1-dioxothian-4-ol;

Chemical Property of tetrahydro-2H-thiopyran-4-ol 1,1-dioxide(SALTDATA: FREE)

Chemical Property:

• Melting Point: 138-138.5 °C
• Boiling Point: 378.1±35.0 °C(Predicted)
• PKA: 13.97±0.20(Predicted)
• PSA: 62.75000
• Density: 1.365±0.06 g/cm3(Predicted)
• LogP: 0.63670
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

4-Hydroxytetrahydro-2H-thiopyran1,1-dioxide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tetrahydro-2H-thiopyran-4-ol 1,1-dioxide(SALTDATA: FREE)

There total 5 articles about tetrahydro-2H-thiopyran-4-ol 1,1-dioxide(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

tetrahydrothiopyran-4-ol (29683-23-6) → 4-hydroxytetrahydro-2H-thiopyrane 1,1-dioxide (194152-05-1)

Guidance literature:

With potassium metaperiodate;

Reference yield:

1,1-dioxotetrahydrothiopyran-4-one (17396-35-9) → 4-hydroxytetrahydro-2H-thiopyrane 1,1-dioxide (194152-05-1)

Guidance literature:

With nickel; at 110 ℃; under 73550.8 Torr; Hydrogenation;

DOI:10.1021/ja01150a020

Reference yield:

Tetrahydrothiopyran-4-one (1072-72-6) → 4-hydroxytetrahydro-2H-thiopyrane 1,1-dioxide (194152-05-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / NaBH₄

2: 98 percent / KIO₄

With sodium tetrahydroborate; potassium metaperiodate;

upstream raw materials:

1,1-dioxotetrahydrothiopyran-4-one

water

tetrahydrothiopyran-4-ol

Tetrahydrothiopyran-4-one

Downstream raw materials:

4-Acetoxythiacyclohexan-1,1-dioxid

4-Bromthiacyclohexan-1,1-dioxid

2-[(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-(4-phenoxy-benzoyl)-amino]-thiazole-5-carboxylic acid ethyl ester

dicyclohexyl-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-phosphane