(4-Chlorophenyl)(3-hydroxyphenyl)methanone

Base Information

Chemical Name:(4-Chlorophenyl)(3-hydroxyphenyl)methanone
CAS No.:62810-39-3
Molecular Formula:C13H9ClO2
Molecular Weight:232.6624
Hs Code.:
NSC Number:109427
DSSTox Substance ID:DTXSID50296456
Wikidata:Q82037073
ChEMBL ID:CHEMBL1886825

Synonyms:(4-chlorophenyl)(3-hydroxyphenyl)methanone;62810-39-3;(4-chlorophenyl)-(3-hydroxyphenyl)methanone;MLS002704160;NSC 109427;NSC109427;SCHEMBL9468917;CHEMBL1886825;DTXSID50296456;MFCD16316859;NSC-109427;SMR001570866

Suppliers and Price of (4-Chlorophenyl)(3-hydroxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of (4-Chlorophenyl)(3-hydroxyphenyl)methanone

Chemical Property:

Vapor Pressure:2.57E-07mmHg at 25°C
Boiling Point:410.3°C at 760 mmHg
Flash Point:201.9°C
Density:1.307g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:232.0291072
Heavy Atom Count:16
Complexity:246

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)O)C(=O)C2=CC=C(C=C2)Cl

Technology Process of (4-Chlorophenyl)(3-hydroxyphenyl)methanone

There total 5 articles about (4-Chlorophenyl)(3-hydroxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 32363-45-4
(4-chlorophenyl)(3-methoxyphenyl)methanone

: 62810-39-3
(4-chlorophenyl)(3-hydroxyphenyl)methanone

Guidance literature:: With hydrogen bromide; acetic acid; In water; at 125 ℃; for 36h;
DOI:10.1021/jm201608g

Reference yield: 45.0%

: 623-03-0
4-Cyanochlorobenzene

: 142402-62-8
(3-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)magnesium bromide

: 62810-39-3
(4-chlorophenyl)(3-hydroxyphenyl)methanone

Guidance literature:: 4-Cyanochlorobenzene; (3-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)magnesium bromide; In tetrahydrofuran; at 75 ℃; for 6h; Inert atmosphere;

With hydrogenchloride; In water; at 20 ℃; for 1h;
DOI:10.1021/acs.jmedchem.9b00279

Reference yield:

: 122334-37-6
4-chloro-N-methoxy-N-methylbenzamide

: 62810-39-3
(4-chlorophenyl)(3-hydroxyphenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / 1 h / -20 °C

1.2: 3.5 h / -78 - 0 °C

2.1: hydrogen bromide; acetic acid / water / 36 h / 125 °C

With hydrogen bromide; isopropylmagnesium chloride; acetic acid; In tetrahydrofuran; water;
DOI:10.1021/jm201608g