4-Chloro-3'-methoxybenzophenone

Base Information

• Chemical Name: 4-Chloro-3'-methoxybenzophenone
• CAS No.: 32363-45-4
• Molecular Formula: C₁₄H₁₁ClO₂
• Molecular Weight: 246.693
• DSSTox Substance ID: DTXSID80373981
• Nikkaji Number: J1.277.689F
• Wikidata: Q82162411
• Mol file: 32363-45-4.mol

Synonyms:4-Chloro-3'-methoxybenzophenone;32363-45-4;(4-chlorophenyl)-(3-methoxyphenyl)methanone;SCHEMBL9278411;3-Methoxy-4'-chlorobenzophenone;DTXSID80373981;MFCD01311567;AKOS009339247;(4-chlorophenyl)(3-methoxyphenyl)methanone;4-chloro-3'-methoxybenzophenone, AldrichCPR;CS-0362960;(4-Chloro-phenyl)-(3-methoxy-phenyl)-methanone

Chemical Property of 4-Chloro-3'-methoxybenzophenone

Chemical Property:

• Vapor Pressure: 4.22E-06mmHg at 25°C
• Boiling Point: 384.0±27.0 °C(Predicted)
• Density: 1.212±0.06 g/cm3(Predicted)
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 246.0447573
• Heavy Atom Count: 17
• Complexity: 259

Purity/Quality:

98%Min ^*data from raw suppliers

4-Chloro-3'-methoxybenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C(=O)C2=CC=C(C=C2)Cl

Technology Process of 4-Chloro-3'-methoxybenzophenone

There total 7 articles about 4-Chloro-3'-methoxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

3-methoxyphenylboronic acid (10365-98-7,1107579-37-2) + 4-chlorobenzaldehyde (104-88-1) → (4-chlorophenyl)(3-methoxyphenyl)methanone (32363-45-4)

Guidance literature:

With potassium phosphate; 3,3-dimethyl-butan-2-one; C₁₄H₁₀Cl₂N₂O₂Ru; tri tert-butylphosphoniumtetrafluoroborate; In water; toluene; at 100 ℃; for 24h;

DOI:10.1016/j.jorganchem.2013.11.019

Reference yield: 56.0%

4-chloro-benzoyl chloride (122-01-0) + tributyl(3-methoxyphenyl)stannane (122439-11-6) → (4-chlorophenyl)(3-methoxyphenyl)methanone (32363-45-4)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; In toluene; at 90 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2012.10.026

Reference yield:

(4-chlorphenyl)magnesium bromide (873-77-8) + 2-bromo-N,5-dimethoxy-N-methylbenzamide (374803-67-5) → (2-bromo-5-methoxyphenyl)(4-chlorophenyl)methanone (746651-89-8) + (4-chlorophenyl)(3-methoxyphenyl)methanone (32363-45-4)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

upstream raw materials:

(4-chlorophenyl)(3-hydroxyphenyl)methanone

dimethyl sulfate

methyl iodide

(4-chlorphenyl)magnesium bromide

Downstream raw materials:

2,2-dimethyl-1,1-diphenyl-propan-1-ol

2,2-dimethyl-1,1-di-p-tolyl-propan-1-ol

C₂₅H₃₂ClNO₃

C₂₅H₃₂ClNO₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 32363-45-4 4-CHLORO-3'-METHOXYBENZOPHENONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send