3-Methylene-3,4-dihydro-2H-1,5-benzodioxepin

Base Information

• Chemical Name: 3-Methylene-3,4-dihydro-2H-1,5-benzodioxepin
• CAS No.: 19560-64-6
• Molecular Formula: C10H10O2
• Molecular Weight: 162.18500
• Hs Code.: 2932999099
• Mol file: 19560-64-6.mol

Synonyms:2,3-Benzo-6-methylen-5,6-dihydro-1,4-dioxepin;3-methylene-3,4-dihydro-2H-1,5-benzodioxepine;3-Methylen-3,4-dihydro-2H-benz-1,5-dioxepin (3-Methylen-1,5-benzodioxepan);3-methylene-1,5-benzodioxepane;

Chemical Property of 3-Methylene-3,4-dihydro-2H-1,5-benzodioxepin

Chemical Property:

• PSA: 18.46000
• LogP: 2.01400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Methylene-3,4-dihydro-2H-1,5-benzodioxepin

There total 5 articles about 3-Methylene-3,4-dihydro-2H-1,5-benzodioxepin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,3-diacetoxy-2-methylenepropane (3775-29-9) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 3-methylene-3,4-dihydro-2H-benzo[b][1,4]dioxepine (19560-64-6)

Guidance literature:

With 1,4-di(diphenylphosphino)-butane; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; at 25 ℃; for 24h;

DOI:10.1055/s-2001-16092

Reference yield: 64.0%

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) + 3-Chloro-2-methylpropene (563-47-3) → 3-methylene-3,4-dihydro-2H-benzo[b][1,4]dioxepine (19560-64-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; butanone; at 80 ℃;

DOI:10.1248/cpb.54.1299

Reference yield:

2-chloromethyl-3-chloroprop-1-ene (1871-57-4) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 3-methylene-3,4-dihydro-2H-benzo[b][1,4]dioxepine (19560-64-6)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide;

upstream raw materials:

1,3-diacetoxy-2-methylenepropane

benzene-1,2-diol

2-chloromethyl-3-chloroprop-1-ene

3-Chloro-2-methylpropene

Downstream raw materials:

2-(2-methoxyallyloxy)phenol

ortho-methallylpyrocatechol