2-Pyridinamine, N-(pentafluorophenyl)-

Base Information

• Chemical Name: 2-Pyridinamine, N-(pentafluorophenyl)-
• CAS No.: 196189-94-3
• Molecular Formula: C11H5F5N2
• Molecular Weight: 260.166
• DSSTox Substance ID: DTXSID90477707
• Nikkaji Number: J1.044.460H
• Mol file: 196189-94-3.mol

Synonyms:2-Pyridinamine, N-(pentafluorophenyl)-;196189-94-3;SCHEMBL2296586;DTXSID90477707

Chemical Property of 2-Pyridinamine, N-(pentafluorophenyl)-

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 260.03728898
• Heavy Atom Count: 18
• Complexity: 264

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)NC2=C(C(=C(C(=C2F)F)F)F)F

Technology Process of 2-Pyridinamine, N-(pentafluorophenyl)-

There total 2 articles about 2-Pyridinamine, N-(pentafluorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-aminopyridine (504-29-0) + Hexafluorobenzene (392-56-3) → 2-( 2,3,4,5,6-pentafluoroanilino)pyridine (196189-94-3)

Guidance literature:

2-aminopyridine; With n-butyllithium; In tetrahydrofuran; hexane; at 25 ℃; for 4h;

Hexafluorobenzene; In tetrahydrofuran; for 24h; Further stages.; Heating;

DOI:10.1002/ejic.200700772

Reference yield: 54.0%

2-bromo-pyridine (109-04-6) + 2,3,4,5,6-pentafluoroaniline (771-60-8) → 2-( 2,3,4,5,6-pentafluoroanilino)pyridine (196189-94-3)

Guidance literature:

at 160 ℃; for 15h;

Reference yield: 97.0%

antimony tris(diethylamide) (34832-65-0) + 2-( 2,3,4,5,6-pentafluoroanilino)pyridine (196189-94-3) → diethylaminobis[N-pentafluorophenyl-N-(2-pyridyl)amino]stibane (802902-73-4)

Guidance literature:

In toluene; (Ar), 2 equiv. of amine in toluene added dropwise at -78°C to a stirrred stibane complex in toluene, stirred at room temp. for 12 h; evapd.(vac.), elem. anal.;

DOI:10.1002/ejic.200400074

upstream raw materials:

2-bromo-pyridine

2,3,4,5,6-pentafluoroaniline

2-aminopyridine

Hexafluorobenzene

Downstream raw materials:

C₁₅H₁₇F₃N₄

C₁₃H₁₁F₄N₃

bis(diethylamino)[N-pentafluorophenyl-N-(2-pyridyl)amino]stibane

diethylaminobis[N-pentafluorophenyl-N-(2-pyridyl)amino]stibane