METHYL 2-(3-(AMINOMETHYL)PHENYL)ACETATE HYDROCHLORIDE

Base Information

• Chemical Name: METHYL 2-(3-(AMINOMETHYL)PHENYL)ACETATE HYDROCHLORIDE
• CAS No.: 197792-60-2
• Molecular Formula: C10H13NO2.ClH
• Molecular Weight: 215.68
• Hs Code.: 2916399090
• Mol file: 197792-60-2.mol

Synonyms:

Chemical Property of METHYL 2-(3-(AMINOMETHYL)PHENYL)ACETATE HYDROCHLORIDE

Chemical Property:

• PSA: 52.32000
• LogP: 2.36310

Purity/Quality:

95% ^*data from raw suppliers

Methyl2-(3-(aminomethyl)phenyl)-acetatehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 2-(3-(AMINOMETHYL)PHENYL)ACETATE HYDROCHLORIDE

There total 2 articles about METHYL 2-(3-(AMINOMETHYL)PHENYL)ACETATE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

→ (3-(2-methoxy-2-oxoethyl)phenyl) methanaminium chloride (197792-60-2)

Guidance literature:

Reference yield: 85.0%

(3-cyano-phenyl)-acetic acid methyl ester (52798-00-2) → (3-(2-methoxy-2-oxoethyl)phenyl) methanaminium chloride (197792-60-2)

Guidance literature:

With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In 1,4-dioxane; methanol; at 20 ℃; for 3h;

Reference yield: 28.0%

(3-(2-methoxy-2-oxoethyl)phenyl) methanaminium chloride (197792-60-2) + 2-butoxy-9-[6-(4-hydroxybutoxy)pyridin-3-yl]methyl-8-methoxy-adenine → 2-butoxy-8-methoxy-9-{6-[4-(3-methoxycarbonylmethylbenzyl)aminobutoxy]pyridin-3-ylmethyl}adenine (930785-13-0)

Guidance literature:

2-butoxy-9-[6-(4-hydroxybutoxy)pyridin-3-yl]methyl-8-methoxy-adenine; With dmap; triethylamine; In tetrahydrofuran; at 20 ℃; for 0.166667h;

With methanesulfonyl chloride; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;

(3-(2-methoxy-2-oxoethyl)phenyl) methanaminium chloride; With potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; at 60 ℃; for 48h;

upstream raw materials:

(3-cyano-phenyl)-acetic acid methyl ester

Downstream raw materials:

2-butoxy-8-methoxy-9-{6-[4-(3-methoxycarbonylmethylbenzyl)aminobutoxy]pyridin-3-ylmethyl}adenine

(3-(((2-(3-chloro-phenoxy)-ethyl)-(pyridine-3-sulfonyl)-amino)-methyl)-phenyl)-acetic acid methyl ester