2-Formylphenyl benzoate

Base Information

• Chemical Name: 2-Formylphenyl benzoate
• CAS No.: 19820-51-0
• Molecular Formula: C14H10O3
• Molecular Weight: 226.232
• DSSTox Substance ID: DTXSID70406353
• Nikkaji Number: J1.413.812I
• Wikidata: Q82211279
• Mol file: 19820-51-0.mol

Synonyms:2-Formylphenyl benzoate;19820-51-0;(2-formylphenyl) Benzoate;Benzaldehyde, 2-(benzoyloxy)-;Benzoylsalicylaldehyd;2-Formylphenylbenzoate;SCHEMBL6374160;DTXSID70406353;MFCD07084068;AKOS000290826

Chemical Property of 2-Formylphenyl benzoate

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 226.062994177
• Heavy Atom Count: 17
• Complexity: 269

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)OC2=CC=CC=C2C=O

Technology Process of 2-Formylphenyl benzoate

There total 13 articles about 2-Formylphenyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

salicylaldehyde (90-02-8) + benzoyl chloride (98-88-4) → 2-benzoyloxy-benzaldehyde (19820-51-0)

Guidance literature:

With pyridine; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4020(01)89848-3

Reference yield: 78.0%

salicylaldehyde (90-02-8) + α-bromoacetophenone (70-11-1) → 2-benzoyloxy-benzaldehyde (19820-51-0)

Guidance literature:

With copper(II) acetate monohydrate; In tert-Amyl alcohol; at 100 ℃; for 12h; Reagent/catalyst; Solvent;

DOI:10.1039/c7cc05383e

Reference yield: 73.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + salicylaldehyde (90-02-8) → 2-benzoyloxy-benzaldehyde (19820-51-0)

Guidance literature:

With tert.-butylhydroperoxide; copper diacetate; In acetonitrile; at 80 ℃; for 15h;

DOI:10.1016/j.tet.2021.132000

upstream raw materials:

salicylaldehyde

benzoyl chloride

sodium salicylate

salicylaldehyde, thallium(I) salt

Refernces

• 1、 ?akmak, Re?it,?entürk, Murat,Ba?aran, Eyüp. "Synthesis, characterization, and biological evaluation of some novel Schiff bases as potential metabolic enzyme inhibitors". . . Retrieved 2022/01/13.
• 2、 Baruah, Swagata,Borthakur, Somadrita,Gogoi, Sanjib. "Directing group assisted copper-mediated aroylation of phenols using 2-bromoacetophenones". supporting information. p. 9133 - 9135. Retrieved 2017/08/17.