3-[(4-Methylpiperazin-1-yl)methyl]aniline

Base Information

Chemical Name:3-[(4-Methylpiperazin-1-yl)methyl]aniline
CAS No.:198281-55-9
Molecular Formula:C12H19N3
Molecular Weight:205.303
Hs Code.:2933599590
DSSTox Substance ID:DTXSID00424409
Wikidata:Q82236975
Mol file:198281-55-9.mol

Synonyms:198281-55-9;3-[(4-methylpiperazin-1-yl)methyl]aniline;3-(4-METHYL-PIPERAZIN-1-YLMETHYL)-ANILINE;3-((4-methylpiperazin-1-yl)methyl)aniline;3-[(4-methyl-1-piperazinyl)methyl]aniline;Benzenamine, 3-[(4-methyl-1-piperazinyl)methyl]-;MFCD06804545;3-(4-Methyl-piperazin-1-ylmethyl)-phenylamine;{3-[(4-Methylpiperazin-1-yl)methyl]phenyl}amine;3-(4-Methyl-piperazin-1-ylmethyl)aniline;3-(4-methylpiperazin-1-ylmethyl)aniline;SCHEMBL62758;3-((4-METHYLPIPERAZIN-1-YL)METHYL) BENZENAMINE;DTXSID00424409;ZGPHZHCPWKOKDX-UHFFFAOYSA-N;AB9788;BBL030691;STL316176;3-(4-methylpiperazinomethyl)-aniline;AKOS000157509;AB30364;HB-5027;1-(3-amino-benzyl)-4-methylpiperazine;SY028808;CS-0208343;FT-0710691;EN300-54413;A813971;J-510738;3-(4-methyl-piperazin-1-ylmethyl)-aniline, AldrichCPR;Z285162780

Suppliers and Price of 3-[(4-Methylpiperazin-1-yl)methyl]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-[(4-methylpiperazin-1-yl)methyl]aniline
500mg
$ 265.00

SynQuest Laboratories
3-[(4-Methylpiperazin-1-yl)methyl]aniline
5 g
$ 792.00

SynQuest Laboratories
3-[(4-Methylpiperazin-1-yl)methyl]aniline
1 g
$ 264.00

Matrix Scientific
3-[(4-Methylpiperazin-1-yl)methyl]aniline >97%
500mg
$ 406.00

Matrix Scientific
3-[(4-Methylpiperazin-1-yl)methyl]aniline >97%
1g
$ 548.00

Chemenu
3-[(4-Methyl-1-piperazinyl)methyl]aniline 95%
25g
$ 655.00

Chemenu
3-[(4-Methyl-1-piperazinyl)methyl]aniline 95%
10g
$ 355.00

Chemenu
3-[(4-Methyl-1-piperazinyl)methyl]aniline 95%
5g
$ 209.00

Atlantic Research Chemicals
3-[(4-methylpiperazin-1-yl)methyl]aniline 95%
1gm:
$ 70.69

Atlantic Research Chemicals
3-[(4-methylpiperazin-1-yl)methyl]aniline 95%
500mgs:
$ 49.48

Total 18 raw suppliers

Chemical Property of 3-[(4-Methylpiperazin-1-yl)methyl]aniline

Chemical Property:

PSA：32.50000
LogP:1.47320
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.157897619
Heavy Atom Count:15
Complexity:187

Purity/Quality:

99%, ^*data from raw suppliers

3-[(4-methylpiperazin-1-yl)methyl]aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)CC2=CC(=CC=C2)N
Uses 3-[(4-Methylpiperazin-1-yl)methyl]aniline is used in preparation of pyrido[3,4-d]pyrimidin-4-ol derivs. as histone demethylase inhibitors.

Technology Process of 3-[(4-Methylpiperazin-1-yl)methyl]aniline

There total 7 articles about 3-[(4-Methylpiperazin-1-yl)methyl]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 198281-54-8
1-methyl-4-(3-nitro-benzyl)-piperazine

: 198281-55-9
3-(4-methyl-piperazin-1-ylmethyl)-phenylamine

Guidance literature:: With hydrogen;

Reference yield: 87.0%

: 1015484-22-6
1-methyl-4-((trifluoro-λ⁴-boranyl)methyl)piperazine potassium

: 108-42-9
3-chloro-aniline

: 198281-55-9
3-(4-methyl-piperazin-1-ylmethyl)-phenylamine

Guidance literature:: With C₅₂H₆₇ClFeNPPd; caesium carbonate; In tetrahydrofuran; water; at 80 ℃; for 12h;
DOI:10.1055/s-0030-1259331

Reference yield:

: 109-01-3
1-methyl-piperazine

: 3958-57-4
1-bromomethyl-3-nitrobenzene

: 198281-55-9
3-(4-methyl-piperazin-1-ylmethyl)-phenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 80 °C

2: water; ammonium chloride / zinc / tetrahydrofuran / 2 h / 20 °C

With water; potassium carbonate; ammonium chloride; zinc; In tetrahydrofuran; N,N-dimethyl-formamide;