2-DIMETHYLAMINOMETHYL-BENZALDEHYDE

Base Information

• Chemical Name: 2-DIMETHYLAMINOMETHYL-BENZALDEHYDE
• CAS No.: 19886-78-3
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• Hs Code.: 2922399090
• Mol file: 19886-78-3.mol

Synonyms:dimethylaminomethyldimethylbenzenol;2-formyl-N,N-dimethylbenzylamine;2-(N,N-dimethylaminomethyl)benzaldehyde;o-(N,N-Dimethylaminomethyl)-benzaldehyde;2-(N,N-dimethylaminomethyl)-4,6-dimethylphenol;2-Dimethylaminomethyl-benzaldehyd;2-Dimethylaminomethyl-4,6-dimethyl-phenol;2-dimethylaminomethylbenzaldehyde;2,4-dimethyl-6-dimethylaminomethylphenol;2-(N,N-dimethylaminomethyl)-4,6-dimethylophenol;

Chemical Property of 2-DIMETHYLAMINOMETHYL-BENZALDEHYDE

Chemical Property:

• PSA: 20.31000
• LogP: 1.56070

Purity/Quality:

97% ^*data from raw suppliers

2-[(Dimethylamino)methyl]benzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-DIMETHYLAMINOMETHYL-BENZALDEHYDE

There total 10 articles about 2-DIMETHYLAMINOMETHYL-BENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N'-dimethylbenzylamine (103-83-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 1-formyl-2-[(dimethylamino)methyl]benzene (19886-78-3)

Guidance literature:

N,N'-dimethylbenzylamine; With tert.-butyl lithium; In diethyl ether; water; Inert atmosphere;

N,N-dimethyl-formamide; In diethyl ether; water; Inert atmosphere;

DOI:10.1002/cmdc.201500349

Reference yield: 25.5%

2-bromo-N,N-dimethylbenzylamine (1976-04-1) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 1-formyl-2-[(dimethylamino)methyl]benzene (19886-78-3)

Guidance literature:

2-bromo-N,N-dimethylbenzylamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h;

Reference yield:

2-((dimethylamino)methyl)benzonitrile (53369-76-9) → 1-formyl-2-[(dimethylamino)methyl]benzene (19886-78-3)

Guidance literature:

2-((dimethylamino)methyl)benzonitrile; With diisobutylaluminium hydride; In tetrahydrofuran; hexane; at -78 ℃; for 2h;

With methanol; In tetrahydrofuran; hexane; at 20 ℃;

upstream raw materials:

N,N-dimethylaminomethylstyrene

2-(dimethylaminocarbonyl)benzoic acid

trans-diiodocyclobutabenzene

dimethyl amine

Downstream raw materials:

2--benzhydrol

3-(2-dimethylaminomethyl-phenyl)-1-phenyl-propan-1-one

2--1,3-dithiane

N,N-dimethyl(2-formylphenyl)methylamine hydrochloride