4-Phenylquinoline-5,8-dione

Base Information

Chemical Name:4-Phenylquinoline-5,8-dione
CAS No.:199281-61-3
Molecular Formula:C15H9NO2
Molecular Weight:235.242
Hs Code.:
DSSTox Substance ID:DTXSID90445087
Nikkaji Number:J905.369G
Wikidata:Q82263418

Synonyms:4-phenylquinoline-5,8-dione;199281-61-3;5,8-Quinolinedione, 4-phenyl-;DTXSID90445087

Suppliers and Price of 4-Phenylquinoline-5,8-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Phenylquinoline-5,8-dione

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:235.063328530
Heavy Atom Count:18
Complexity:382

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C3C(=O)C=CC(=O)C3=NC=C2

Technology Process of 4-Phenylquinoline-5,8-dione

There total 3 articles about 4-Phenylquinoline-5,8-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 199281-59-9
5,8-dimethoxy-4-phenylquinoline

: 199281-61-3
4-Phenyl-quinoline-5,8-dione

Guidance literature:: With Pyridine-2,6-dicarboxylic acid N-oxide; ammonium cerium(IV) nitrate; In water; acetonitrile; at 0 - 5 ℃; for 0.5h;
DOI:10.1248/cpb.45.1697

Reference yield:

: 934-56-5
trimethyl(phenyl)stannane

: 199281-61-3
4-Phenyl-quinoline-5,8-dione

Guidance literature:: Multi-step reaction with 2 steps

1: copper(I) bromide; tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dioxane / 1.5 h / 90 °C

2: ammonium cerium(IV) nitrate; sulfuric acid / acetonitrile / 3 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; ammonium cerium(IV) nitrate; sulfuric acid; copper(I) bromide; In 1,4-dioxane; acetonitrile; 1: Stille coupling;
DOI:10.1016/j.bmc.2004.09.021

Reference yield:

: 114552-21-5
5,8-dimethoxy-4-trifluoromethansulfonyloxyquinoline

: 199281-61-3
4-Phenyl-quinoline-5,8-dione

Guidance literature:: Multi-step reaction with 2 steps

1: copper(I) bromide; tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dioxane / 1.5 h / 90 °C

2: ammonium cerium(IV) nitrate; sulfuric acid / acetonitrile / 3 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; ammonium cerium(IV) nitrate; sulfuric acid; copper(I) bromide; In 1,4-dioxane; acetonitrile; 1: Stille coupling;
DOI:10.1016/j.bmc.2004.09.021