3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

Base Information

• Chemical Name: 3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide
• CAS No.: 14471-83-1
• Molecular Formula: C₁₅H₁₃F₄N₃O₄S₂
• Molecular Weight: 439.412
• Mol file: 14471-83-1.mol

Synonyms:

Chemical Property of 3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

There total 2 articles about 3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide (654-62-6) + 1-(4-fluorophenyl)ethane-1,2-diol (17951-22-3,179694-35-0) → 3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ6-benzo[1,2,4]thiadiazine-7-sulfonic acid amide (14471-83-1)

Guidance literature:

With sulfuric acid; Heating;

Reference yield:

4-amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide (654-62-6) + para-fluorostyrene (405-99-2) → 3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ6-benzo[1,2,4]thiadiazine-7-sulfonic acid amide (14471-83-1)

Guidance literature:

Multistep reaction; (i) aq. H₂O₂, HCO₂H, (ii) /BRN= 1164542/, aq. H₂SO₄;

upstream raw materials:

4-amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide

para-fluorostyrene

1-(4-fluorophenyl)ethane-1,2-diol