[3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol

Base Information

Chemical Name:[3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol
CAS No.:203634-91-7
Molecular Formula:C10H10BrNO2
Molecular Weight:256.099
Hs Code.:
DSSTox Substance ID:DTXSID60579146
Nikkaji Number:J3.614.331B

Synonyms:203634-91-7;[3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol;(3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl)methanol;SCHEMBL3326724;DTXSID60579146;GGIWECLXRZECPP-UHFFFAOYSA-N;[3-(4-Bromophenyl)-4,5-dihydro-1,2-oxazol-5-yl]methanol;AKOS013484451;[3-(4-bromophenyl)-4,5-dihydroisoxazol-5-yl]-methanol;[3-(4-Bromo-phenyl)-4,5-dihydro-isoxazol-5-yl]-methanol;(5RS)-[3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol;(5RS)-3-(4-Bromophenyl)-5-hydroxymethyl-4,5-dihydro-isoxazole

Suppliers and Price of [3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of [3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:254.98949
Heavy Atom Count:14
Complexity:224

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(ON=C1C2=CC=C(C=C2)Br)CO

Technology Process of [3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol

There total 9 articles about [3-(4-Bromophenyl)-4,5-dihydroisoxazol-5-yl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 107-18-6
allyl alcohol

: 29203-58-5
4-bromo-N-hydroxybenzenecarboximidoyl chloride

: 203634-91-7
4,5-dihydro[3-(4-bromophenyl)-5-(hydroxymethyl)]isoxazole

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jm020248u

Reference yield: 65.0%

: 1-(4-bromophenyl)but-3-en-1-one oxime

: 203634-91-7
4,5-dihydro[3-(4-bromophenyl)-5-(hydroxymethyl)]isoxazole

Guidance literature:: With 2,2,2-Trifluoroacetophenone; dihydrogen peroxide; In water; acetonitrile; tert-butyl alcohol; at 20 ℃; for 18h; Green chemistry;
DOI:10.1021/acs.orglett.6b03380

Reference yield: 37.0%

: 1122-91-4
4-bromo-benzaldehyde

: 107-18-6
allyl alcohol

: 203634-91-7
4,5-dihydro[3-(4-bromophenyl)-5-(hydroxymethyl)]isoxazole

Guidance literature:: 4-bromo-benzaldehyde; With toluene-4-sulfonic acid hydrazide;

allyl alcohol; With tert.-butylnitrite; N,N,N,N,-tetramethylethylenediamine; copper dichloride; In tetrahydrofuran; at 65 ℃; for 24h;
DOI:10.1039/d1sc02352g