4-(Dimethylamino)cyclohexanone O-(4-nitrophenyl)oxime

Base Information

Chemical Name:4-(Dimethylamino)cyclohexanone O-(4-nitrophenyl)oxime
CAS No.:203985-56-2
Molecular Formula:C14H19N3O3
Molecular Weight:277.323
Hs Code.:
DSSTox Substance ID:DTXSID601214044

Synonyms:DTXSID601214044;4-(Dimethylamino)cyclohexanone O-(4-nitrophenyl)oxime;203985-56-2

Suppliers and Price of 4-(Dimethylamino)cyclohexanone O-(4-nitrophenyl)oxime

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(Dimethylamino)cyclohexanone O-(4-nitrophenyl)oxime

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:277.14264148
Heavy Atom Count:20
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C1CCC(=NOC2=CC=C(C=C2)[N+](=O)[O-])CC1

Technology Process of 4-(Dimethylamino)cyclohexanone O-(4-nitrophenyl)oxime

There total 4 articles about 4-(Dimethylamino)cyclohexanone O-(4-nitrophenyl)oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 203985-55-1
4-dimethylaminocyclohexanone oxime

: 203985-56-2
4-dimethylaminocyclohexanone O-(4-nitrophenyl)oxime

Guidance literature:: With 18-crown-6 ether; potassium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h;
DOI:10.1021/jo020600b

Reference yield:

: 4746-97-8
cyclohexanedione monoethylene ketal

: 203985-56-2
4-dimethylaminocyclohexanone O-(4-nitrophenyl)oxime

Guidance literature:: Multi-step reaction with 4 steps

1: glacial acetic acid; sodium triacetoxyborohydride / CH₂Cl₂; tetrahydrofuran / 10 - 20 °C

2: 119 g / hydrochloric acid / H₂O / 1 h / Heating

3: 87 percent / hydroxylamine hydrochloride; pyridine / ethanol / 3 h / Heating

4: 90 percent / potassium hydride; 18-crown-6 / tetrahydrofuran / 3 h / 0 - 20 °C

With pyridine; hydrogenchloride; 18-crown-6 ether; hydroxylamine hydrochloride; potassium hydride; sodium tris(acetoxy)borohydride; acetic acid; In tetrahydrofuran; ethanol; dichloromethane; water;
DOI:10.1021/jo020600b

Reference yield:

: 40594-34-1
4-(dimethylamino)cyclohexanone

: 203985-56-2
4-dimethylaminocyclohexanone O-(4-nitrophenyl)oxime

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / hydroxylamine hydrochloride; pyridine / ethanol / 3 h / Heating

2: 90 percent / potassium hydride; 18-crown-6 / tetrahydrofuran / 3 h / 0 - 20 °C

With pyridine; 18-crown-6 ether; hydroxylamine hydrochloride; potassium hydride; In tetrahydrofuran; ethanol;
DOI:10.1021/jo020600b