(4S)-4-tert-Butyl-3-(phenylacetyl)-1,3-oxazolidin-2-one

Base Information

Chemical Name:(4S)-4-tert-Butyl-3-(phenylacetyl)-1,3-oxazolidin-2-one
CAS No.:204851-46-7
Molecular Formula:C15H19NO3
Molecular Weight:261.321
Hs Code.:
DSSTox Substance ID:DTXSID90582062
Nikkaji Number:J2.373.167C
Wikidata:Q82473389

Synonyms:204851-46-7;DTXSID90582062;(4S)-4-tert-Butyl-3-(phenylacetyl)-1,3-oxazolidin-2-one

Suppliers and Price of (4S)-4-tert-Butyl-3-(phenylacetyl)-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (4S)-4-tert-Butyl-3-(phenylacetyl)-1,3-oxazolidin-2-one

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:261.13649347
Heavy Atom Count:19
Complexity:353

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1COC(=O)N1C(=O)CC2=CC=CC=C2
Isomeric SMILES:CC(C)(C)[C@H]1COC(=O)N1C(=O)CC2=CC=CC=C2

Technology Process of (4S)-4-tert-Butyl-3-(phenylacetyl)-1,3-oxazolidin-2-one

There total 1 articles about (4S)-4-tert-Butyl-3-(phenylacetyl)-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 54705-42-9
(S)-4-tert-butyloxazolidin-2-one

: 501-53-1,94274-21-2
benzyl chloroformate

: 204851-46-7
(S)-4-tert-butyl-3-(2'-phenylacetyl)oxazolidin-2-one

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h;
DOI:10.1039/b605244d

Reference yield: 51.0%

: 204851-46-7
(S)-4-tert-butyl-3-(2'-phenylacetyl)oxazolidin-2-one

: 74-88-4
methyl iodide

: (4S,2'S)-4-tert-butyl-3-(2'-phenylpropionyl)oxazolidin-2-one

Guidance literature:: (S)-4-tert-butyl-3-(2'-phenylacetyl)oxazolidin-2-one; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 0 ℃; for 2.5h;

methyl iodide; In tetrahydrofuran; at 0 ℃; for 0.5h; Further stages.;
DOI:10.1039/b605244d

Reference yield:

: 204851-46-7
(S)-4-tert-butyl-3-(2'-phenylacetyl)oxazolidin-2-one

: 17126-67-9,28845-94-5
(+)-(R)-tropic acid

Guidance literature:: Multi-step reaction with 2 steps

2: H₂O₂, LiOH / tetrahydrofuran; H₂O / 3 h / Ambient temperature

With lithium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water;
DOI:10.1021/jo9720804