Butanoic acid, 2-[bis(phenylmethyl)amino]-, methyl ester, (2R)-

Base Information

Chemical Name:Butanoic acid, 2-[bis(phenylmethyl)amino]-, methyl ester, (2R)-
CAS No.:205748-36-3
Molecular Formula:C19H23NO2
Molecular Weight:297.397
Hs Code.:
DSSTox Substance ID:DTXSID20444149
Wikidata:Q82262183

Synonyms:205748-36-3;Butanoic acid, 2-[bis(phenylmethyl)amino]-, methyl ester, (2R)-;SCHEMBL3854880;DTXSID20444149

Suppliers and Price of Butanoic acid, 2-[bis(phenylmethyl)amino]-, methyl ester, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Butanoic acid, 2-[bis(phenylmethyl)amino]-, methyl ester, (2R)-

Chemical Property:

Boiling Point:385.5±30.0 °C(Predicted)
PSA：29.54000
Density:1.075±0.06 g/cm3(Predicted)
LogP:3.64040
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:297.172878976
Heavy Atom Count:22
Complexity:299

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C(=O)OC)N(CC1=CC=CC=C1)CC2=CC=CC=C2
Isomeric SMILES:CC[C@H](C(=O)OC)N(CC1=CC=CC=C1)CC2=CC=CC=C2

Technology Process of Butanoic acid, 2-[bis(phenylmethyl)amino]-, methyl ester, (2R)-

There total 4 articles about Butanoic acid, 2-[bis(phenylmethyl)amino]-, methyl ester, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 124-41-4
sodium methylate

: 205748-35-2
(S)-3-((R)-2-Dibenzylamino-butyryl)-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester

: 205748-36-3
methyl (R)-2-(N,N-dibenzylamino)butanoate

Guidance literature:: In methanol; at 20 ℃; for 3h;
DOI:10.1021/jo9712714

Reference yield:

: 100-39-0
benzyl bromide

: 205748-36-3
methyl (R)-2-(N,N-dibenzylamino)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / potassium carbonate; Bu₄NI / tetrahydrofuran / 48 h

2: 94 percent / methanol / 3 h / 20 °C

With tetra-(n-butyl)ammonium iodide; potassium carbonate; In tetrahydrofuran; methanol; 1: Alkylation / 2: Substitution;
DOI:10.1021/jo9712714

Reference yield:

: 166903-69-1
tert-Butyl (4S)-3-<(2R)-2-(N-benzylamino)butyryl>-1-methyl-2-oxoimidazolidine-4-carboxylate

: 205748-36-3
methyl (R)-2-(N,N-dibenzylamino)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / potassium carbonate; Bu₄NI / tetrahydrofuran / 48 h

2: 94 percent / methanol / 3 h / 20 °C

With tetra-(n-butyl)ammonium iodide; potassium carbonate; In tetrahydrofuran; methanol; 1: Alkylation / 2: Substitution;
DOI:10.1021/jo9712714