(6-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxin-8-yl)methanol

Base Information

Chemical Name:(6-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxin-8-yl)methanol
CAS No.:206879-83-6
Molecular Formula:C11H13BrO3
Molecular Weight:273.12300
Hs Code.:
DSSTox Substance ID:DTXSID70441845
Wikidata:Q82258818
Mol file:206879-83-6.mol

Synonyms:206879-83-6;(6-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxin-8-yl)methanol;(6-BROMO-2,2-DIMETHYL-4H-1,3-BENZODIOXIN-8-YL)METHANOL;SCHEMBL2616010;DTXSID70441845

Suppliers and Price of (6-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxin-8-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (6-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxin-8-yl)methanol

Chemical Property:

Boiling Point:387.9±42.0 °C(Predicted)
PKA:14.00±0.10(Predicted)
PSA：38.69000
Density:1.462±0.06 g/cm3(Predicted)
LogP:2.58650
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:272.00481
Heavy Atom Count:15
Complexity:232

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OCC2=C(O1)C(=CC(=C2)Br)CO)C

Technology Process of (6-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxin-8-yl)methanol

There total 1 articles about (6-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxin-8-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 6296-63-5
4-bromo-2,6-bis(hydroxymethyl)phenol

: 77-76-9
2,2-dimethoxy-propane

: 206879-83-6
6-bromo-2,2-(dimethyl-4H-benzo[a][1,3]dioxin-8-yl)methanol

Guidance literature:: With toluene-4-sulfonic acid; In acetone; for 3h; Ambient temperature;
DOI:10.1021/jo971945a

Reference yield: 55.0%

: 206879-83-6
6-bromo-2,2-(dimethyl-4H-benzo[a][1,3]dioxin-8-yl)methanol

: 206879-95-0
6-bromo-8-(bromomethyl)-2,2-dimethyl-4H-benzo[a][1,3]dioxine

Guidance literature:: With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 49h; Darkness;

Reference yield:

: 206879-83-6
6-bromo-2,2-(dimethyl-4H-benzo[a][1,3]dioxin-8-yl)methanol

: 792959-49-0
C₃₉H₃₄O₉S₃

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / aq. sodium carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / benzene; ethanol / 16 h / Heating

2: 90 percent / aq. HCl / methanol / 12 h / 20 °C

3: 50 percent / aq. NaOH / tetrahydrofuran / 4 h / 0 °C

With hydrogenchloride; sodium hydroxide; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; methanol; ethanol; benzene;
DOI:10.1002/anie.200453914