1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

Base Information

Chemical Name:1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one
CAS No.:20886-48-0
Molecular Formula:C12H15NO
Molecular Weight:189.257
Hs Code.:
DSSTox Substance ID:DTXSID40554279
Wikidata:Q82435216

Synonyms:1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one;20886-48-0;SCHEMBL6748962;DTXSID40554279;GVCMFAGYMNVFSA-UHFFFAOYSA-N;3,4-dihydro-1,4,4-trimethyl-2(1H)-quinolinone

Suppliers and Price of 1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:189.115364102
Heavy Atom Count:14
Complexity:247

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(=O)N(C2=CC=CC=C21)C)C

Technology Process of 1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

There total 1 articles about 1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 135579-08-7
3-Methyl-but-3-enoic acid (2-iodo-phenyl)-methyl-amide

: 20886-48-0
1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

: N-methyl-N-phenyl-methbutylamide

Guidance literature:: With tributyltin chloride; sodium cyanoborohydride; In tert-butyl alcohol; for 12h; Yield given. Yields of byproduct given; Heating;
DOI:10.1016/0040-4039(91)85099-Q

Reference yield: 99.0%

: 20886-48-0
1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

: 100-39-0
benzyl bromide

: 1253231-31-0
3-benzyl-1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

Guidance literature:: 1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -10 ℃; for 0.5h; Inert atmosphere;

benzyl bromide; In tetrahydrofuran; n-heptane; ethylbenzene; at -10 ℃; for 2h; Inert atmosphere;
DOI:10.3390/molecules15117742

Reference yield: 99.0%

: 20886-48-0
1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one

: 100-52-7
benzaldehyde

: 1253231-37-6
3-(hydroxy(phenyl)methyl)-1,4,4-trimethyl-3,4-dihydroquinolin2(1H)-one

Guidance literature:: 1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -10 ℃; for 0.5h; Inert atmosphere;

benzaldehyde; In tetrahydrofuran; n-heptane; ethylbenzene; at -10 ℃; for 2h; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; n-heptane; ethylbenzene; at 20 ℃; Inert atmosphere;
DOI:10.3390/molecules15117742