1,1,3,3-Tetraethoxy-2-methylpropane

Base Information

• Chemical Name: 1,1,3,3-Tetraethoxy-2-methylpropane
• CAS No.: 10602-37-6
• Molecular Formula: C12H26O4
• Molecular Weight: 234.336
• Hs Code.: 2909199090
• European Community (EC) Number: 234-225-2
• UNII: T2853P7X59
• DSSTox Substance ID: DTXSID60147480
• Nikkaji Number: J35.928I
• Wikidata: Q72504955
• Mol file: 10602-37-6.mol

Synonyms:1,1,3,3-Tetraethoxy-2-methylpropane;10602-37-6;EINECS 234-225-2;2-Methyl-1,1,3,3-tetraethoxypropane;1,1,3,3-tetraethoxy-2-methyl-propane;T2853P7X59;Propane, 1,1,3,3-tetraethoxy-2-methyl-;Propane,1,1,3,3-tetraethoxy-2-methyl-;Temp;SCHEMBL358984;UNII-T2853P7X59;DTXSID60147480;AMY37979;MFCD00541470;1.1.3.3-tetraethoxy-2-methylpropane;AKOS015838726;Methylmalonaldehyde Tetraethyl Diacetal;SS-2445;1,1,3,3-tetra-ethoxy-2-methylpropane;1,1,3,3-Tetraethoxy-2-Methyl Propane,,,;EN300-43613;E78367;A934449;J-001526;Z443355572

Chemical Property of 1,1,3,3-Tetraethoxy-2-methylpropane

Chemical Property:

• Vapor Pressure: 0.00983mmHg at 25°C
• Boiling Point: 273°Cat760mmHg
• Flash Point: 52.1°C
• PSA: 36.92000
• Density: 0.925g/cm³
• LogP: 2.42070
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 10
• Exact Mass: 234.18310931
• Heavy Atom Count: 16
• Complexity: 124

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,1,3,3-Tetraethoxy-2-methyl-propane ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C(C)C(OCC)OCC)OCC
• Uses: 1,1,3,3-Tetraethoxy-2-methyl-propane is a useful synthetic intermediate. It used to synthesize various compounds such as Imidazo[1,2-a]pyrimidine, and chlorinated arenes.

Technology Process of 1,1,3,3-Tetraethoxy-2-methylpropane

There total 10 articles about 1,1,3,3-Tetraethoxy-2-methylpropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

diethoxymethyl acetate (14036-06-7) + (Z)-1-ethoxyprop-1-ene (4696-25-7) + orthoformic acid triethyl ester (122-51-0) → 1,1,3,3-tetraethoxy-2-methyl-propane (10602-37-6)

Guidance literature:

With trifluoroborane diethyl ether;

Reference yield: 90.0%

(Z)-1-ethoxyprop-1-ene (4696-25-7) + orthoformic acid triethyl ester (122-51-0) → 1,1,3,3-tetraethoxy-2-methyl-propane (10602-37-6)

Guidance literature:

With FeCl₃;

Reference yield: 88.0%

ethyl 1-propenyl ether (928-55-2) + orthoformic acid triethyl ester (122-51-0) → 1,1,3,3-tetraethoxy-2-methyl-propane (10602-37-6)

Guidance literature:

ethyl 1-propenyl ether; orthoformic acid triethyl ester; With boron trifluoride diethyl etherate; at 45 ℃; for 1h;

With sodium carbonate; at 45 ℃; for 3h;

DOI:10.1021/ja038353w

upstream raw materials:

ethyl 1-propenyl ether

orthoformic acid triethyl ester

ethanol

1,3-dichloro-3-ethoxy-2-methyl-propene

Downstream raw materials:

5-methyl-2-hydroxyacetophenone

2-hydroxy-5-methylbenzophenone

1-(2-hydroxy-3,5-dimethylphenyl)-1-propanone

ethyl 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate

Refernces

• 1、 -. "ULTRAPURE 4-METHYLPYRAZOLE". Page/Page column 2; 3. . Retrieved 2008/06/13.
• 2、 Zaitsev,Dalinger,Starosotnikov,Kachala,Strelenko,Shkineva,Shevelev. "Nitropyrazoles: XII. Transformations of the 4-methyl group in 1,4-dimethyl-3,5-dinitropyrazole and cyclization of the transformation products". . p. 1507 - 1515. Retrieved 2007/10/03.