Methyl (2R)-2-[[(4-methylphenyl)sulfonyl]amino]-4-pentynoate

Base Information

Chemical Name:Methyl (2R)-2-[[(4-methylphenyl)sulfonyl]amino]-4-pentynoate
CAS No.:211054-04-5
Molecular Formula:C13H15NO4S
Molecular Weight:281.332
Hs Code.:
DSSTox Substance ID:DTXSID301184848

Synonyms:DTXSID301184848;Methyl (2R)-2-[[(4-methylphenyl)sulfonyl]amino]-4-pentynoate;211054-04-5

Suppliers and Price of Methyl (2R)-2-[[(4-methylphenyl)sulfonyl]amino]-4-pentynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of Methyl (2R)-2-[[(4-methylphenyl)sulfonyl]amino]-4-pentynoate

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:281.07217913
Heavy Atom Count:19
Complexity:449

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC(CC#C)C(=O)OC
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)N[C@H](CC#C)C(=O)OC

Technology Process of Methyl (2R)-2-[[(4-methylphenyl)sulfonyl]amino]-4-pentynoate

There total 3 articles about Methyl (2R)-2-[[(4-methylphenyl)sulfonyl]amino]-4-pentynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23235-01-0,23235-03-2,50428-03-0,64165-64-6
(R)-2-aminopent-4-ynoic acid

: 211054-04-5
(R)-2-(Toluene-4-sulfonylamino)-pent-4-ynoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂

2: pyridine

With pyridine; thionyl chloride;
DOI:10.1016/S0040-4039(98)00910-1

Reference yield:

: 718596-26-0
2-amino-4-pentynoic acid amide

: 211054-04-5
(R)-2-(Toluene-4-sulfonylamino)-pent-4-ynoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1) aminopeptidase from Pseudomonas putida, 2) 2 M HCl / 1) H₂O, 60 h, 37 deg C, pH 8.5, 2) 90 deg C, 2 h

2: SOCl₂

3: pyridine

With pyridine; hydrogenchloride; thionyl chloride; aminopeptidase from Pseudomonas putida;
DOI:10.1016/S0040-4039(98)00910-1