4-(1,1-diMethylethyl)-iMidazole

Base Information

• Chemical Name: 4-(1,1-diMethylethyl)-iMidazole
• CAS No.: 21149-98-4
• Molecular Formula: C7H12N2
• Molecular Weight: 124.186
• Hs Code.: 2933290090
• Mol file: 21149-98-4.mol

Synonyms:DL-4-TBU-PHE-OH;4-tert-butylimidazole;2-AMINO-3-[4-(TERT-BUTYL)PHENYL]PROPANOIC ACID;4-tert-butyl-1(3)H-imidazole;4-tBu-imidazole;4-(1,1-dimethyethyl)-imidazole;4-tert-Butyl-1(3)H-imidazol;4-(1,1-dimethylethyl)-imidazole;4-tert-butyl-DL-Phenylalanine;

Chemical Property of 4-(1,1-diMethylethyl)-iMidazole

Chemical Property:

• PSA: 28.68000
• LogP: 1.70720

Purity/Quality:

97% ^*data from raw suppliers

5-tert-Butyl-1H-imidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(1,1-diMethylethyl)-iMidazole

There total 8 articles about 4-(1,1-diMethylethyl)-iMidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

formamide (77287-34-4,77287-35-5,60100-09-6) + 1-Bromopinacolon (5469-26-1) → 4-(1,1-dimethylethyl)-imidazole (21149-98-4)

Guidance literature:

at 160 - 180 ℃; for 5h; Sealed tube;

Reference yield: 80.0%

formamidine acetic acid (3473-63-0) + 1-Bromopinacolon (5469-26-1) → tert-butyl imidazole (21149-98-4)

Guidance literature:

With potassium carbonate; at 140 - 180 ℃;

Reference yield: 78.0%

5-tert-butyl-4-tosyl-2-oxazoline → 4-(1,1-dimethylethyl)-imidazole (21149-98-4)

Guidance literature:

With ammonia; In methanol; at 90 - 110 ℃; for 20h;

upstream raw materials:

3,3-dimethyl-butan-2-one

formamide

1-Bromopinacolon

pivalaldehyde

Downstream raw materials:

1-(4-cyanophenyl)-4-(1,1-dimethyethyl)-imidazole

{Fe(C₃H₃N₂C(CH₃)3)(C₇₄H₆₄N₁₂O₄)}*(CH₃)2CO

4-(1,1-dimethylethyl)-1-(4-cyanophenyl)-1-methyl-1H-imidazolium iodide