Ethanone, 2-chloro-1-phenyl-, oxime

Base Information

• Chemical Name: Ethanone, 2-chloro-1-phenyl-, oxime
• CAS No.: 21572-32-7
• Molecular Formula: C8H8ClNO
• Molecular Weight: 169.611
• DSSTox Substance ID: DTXSID90393433
• Mol file: 21572-32-7.mol

Synonyms:Ethanone, 2-chloro-1-phenyl-, oxime;N-(2-chloro-1-phenylethylidene)hydroxylamine;21572-32-7;SCHEMBL8847229;2-Chloro-1-phenylethanone oxime;DTXSID90393433

Chemical Property of Ethanone, 2-chloro-1-phenyl-, oxime

Chemical Property:

• PSA: 32.59000
• LogP: 2.10370
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 169.0294416
• Heavy Atom Count: 11
• Complexity: 141

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NO)CCl

Technology Process of Ethanone, 2-chloro-1-phenyl-, oxime

There total 3 articles about Ethanone, 2-chloro-1-phenyl-, oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → 2-chloro-1-phenyl-ethanone oxime (21572-32-7)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In methanol;

Reference yield: 97.0%

ethyl acetohydroximate (10576-12-2) + 1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → 2-chloro-1-phenyl-ethanone oxime (21572-32-7)

Guidance literature:

With perchloric acid; In ethanol; for 24h; Reflux; Inert atmosphere; Green chemistry;

DOI:10.1039/c6gc02156e

Reference yield: 70.0%

ethyl methyl ketone oxime (96-29-7) + 1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → 2-chloro-1-phenyl-ethanone oxime (21572-32-7)

Guidance literature:

With perchloric acid; In ethanol; for 24h; Reagent/catalyst; Reflux; Inert atmosphere; Green chemistry;

DOI:10.1039/c6gc02156e

upstream raw materials:

1-chloroacetophenone

ethyl methyl ketone oxime

ethyl acetohydroximate

Downstream raw materials:

9-methyl-3-phenyl-4,4a,9,9a-tetrahydro-4a,9a-butano<1,2>oxazino<6,5-b>indole

8-methyl-2-phenyl-3,3a,8,8a-tetrahydro-3a,8a-butanopyrrolo<2,3-b>indole 1-oxide

6-methyl-2,11a-diphenyl-4,5a,6,10b,11,11a-hexahydro-5a,10b-butano-3H-imidazo<1',2':2,3><1,2>oxazino<6,5-b>indole 1-oxide

5,5,6-trimethyl-5,6-dihydro-3-phenyl-6-(trimethylsiloxy)-4H-1,2-oxazine