3-Phenyl-2H-azirine-2-carboxaldehyd

Base Information

• Chemical Name: 3-Phenyl-2H-azirine-2-carboxaldehyd
• CAS No.: 42970-55-8
• Molecular Formula: C9H7 N O
• Molecular Weight: 145.161
• Mol file: 42970-55-8.mol

Synonyms:2-Formyl-3-phenyl-2H-azirine;2-Formyl-3-phenyl-2H-azirine-N-arylimine;3-Phenyl-2H-azirine-2-carboxaldehyde;NSC 255225;

Chemical Property of 3-Phenyl-2H-azirine-2-carboxaldehyd

Chemical Property:

• Vapor Pressure: 0.0138mmHg at 25°C
• Melting Point: 45-47 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• Refractive Index: 1.617
• Boiling Point: 258.3°C at 760 mmHg
• PKA: 2.05±0.40(Predicted)
• Flash Point: 102.9°C
• PSA: 29.43000
• Density: 1.18g/cm³
• LogP: 0.49240

Purity/Quality:

97% ^*data from raw suppliers

3-PHENYL-2H-AZIRENE-2-CARBALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Phenyl-2H-azirine-2-carboxaldehyd

There total 10 articles about 3-Phenyl-2H-azirine-2-carboxaldehyd which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

C9H7N3O → 3-phenyl-2H-azirine-2-carboxaldehyde (42970-55-8)

Guidance literature:

In toluene; at 60 ℃; for 2.5h;

DOI:10.1021/acs.orglett.8b03378

Reference yield: 68.0%

(Z)-β-bromocinnamaldehyde (14804-59-2,33603-88-2) → 3-phenyl-2H-azirine-2-carboxaldehyde (42970-55-8) + 3-phenylisoxazole (1006-65-1)

Guidance literature:

With sodium azide; In dimethyl sulfoxide; at 10 - 30 ℃; for 0.333333h;

DOI:10.1016/j.tetlet.2005.07.086

Reference yield: 68.0%

(Z)-β-bromocinnamaldehyde (14804-59-2,33603-88-2) → 3-phenyl-2H-azirine-2-carboxaldehyde (42970-55-8) + 3-phenylisoxazole (1006-65-1)

Guidance literature:

With sodium azide; In dimethyl sulfoxide; at 10 - 30 ℃; for 0.333333h;

DOI:10.1002/jhet.5570450203

upstream raw materials:

(Z)-3-azido-3-phenylprop-2-en-1-ol

(Z)-3-chloro-3-phenyl-2-propenal

(Z)-β-bromocinnamaldehyde

rac-(2R,3S)-2,3-dibromo-3-phenylpropan-1-ol

Downstream raw materials:

3-phenylisoxazole

4-phenyl-1,3-oxazole

dimethyl 4-phenyl-2H-1,3-oxazine-2,2-dicarboxylate

ethyl 2-cyano-4-phenyl-2H-1,3-oxazine-2-carboxylate