4',6-Dihydroxy-5,7-dimethoxyflavanone

Base Information

• Chemical Name: 4',6-Dihydroxy-5,7-dimethoxyflavanone
• CAS No.: 6951-57-1
• Molecular Formula: C₁₇H₁₆O₆
• Molecular Weight: 316.31
• NSC Number: 56293
• DSSTox Substance ID: DTXSID601139335
• Nikkaji Number: J2.791.382B
• Wikidata: Q27148576
• ChEMBL ID: CHEMBL485056
• Mol file: 6951-57-1.mol

Synonyms:4',6-Dihydroxy-5,7-dimethoxyflavanone;6951-57-1;NSC 56293;6-Hydroxy-2-(4-hydroxyphenyl)-5,7-dimethoxy-2,3-dihydro-4H-chromen-4-one;CHEBI:79493;NSC56293;2,3-Dihydro-6-hydroxy-2-(4-hydroxyphenyl)-5,7-dimethoxy-4H-1-benzopyran-4-one;NSC-56293;6-hydroxy-2-(4-hydroxyphenyl)-5,7-dimethoxy-2,3-dihydrochromen-4-one;6,4'-Dihydroxy-5,7-dimethoxyflavanone;CHEMBL485056;DTXSID601139335;AKOS040734497;Q27148576;6-hydroxy-2-(4-hydroxyphenyl)-5,7-dimethoxy-chroman-4-one

Chemical Property of 4',6-Dihydroxy-5,7-dimethoxyflavanone

Chemical Property:

• Vapor Pressure: 3.84E-14mmHg at 25°C
• Boiling Point: 582°C at 760 mmHg
• Flash Point: 217.8°C
• Density: 1.358g/cm³
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 316.09468823
• Heavy Atom Count: 23
• Complexity: 419

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=C2C(=O)CC(OC2=C1)C3=CC=C(C=C3)O)OC)O

Technology Process of 4',6-Dihydroxy-5,7-dimethoxyflavanone

There total 2 articles about 4',6-Dihydroxy-5,7-dimethoxyflavanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,6-dihydroxy-2,4-dimethoxyacetophenone (6962-57-8) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 6,4'-Dihydroxy-5,7-dimethoxy-flavanon-(4) (6951-57-1)

Guidance literature:

With potassium hydroxide; Ansaeuern des Reaktionsgemisches mit wss. Salzsaeure;

Reference yield:

→ 6,4'-Dihydroxy-5,7-dimethoxy-flavanon-(4) (6951-57-1)

Guidance literature:

4,3',6'-Trihydroxy-8',4'-dimethoxy-chalkon in Me., Eintragen von kochendem W.;

DOI:10.1002/jps.2600530218

upstream raw materials:

3,6-dihydroxy-2,4-dimethoxyacetophenone

4-hydroxy-benzaldehyde