2-[(4-Chloroanilino)(phenyl)methyl]cyclohexanone

Base Information

Chemical Name:2-[(4-Chloroanilino)(phenyl)methyl]cyclohexanone
CAS No.:21854-73-9
Molecular Formula:C19H20ClNO
Molecular Weight:313.827
Hs Code.:
DSSTox Substance ID:DTXSID10451903
Nikkaji Number:J1.344.758F
ChEMBL ID:CHEMBL1479411
Mol file:21854-73-9.mol

Synonyms:2-[(4-chloroanilino)(phenyl)methyl]cyclohexanone;21854-73-9;2-[(4-chloroanilino)-phenylmethyl]cyclohexan-1-one;SMR000161708;MLS000537189;HMS2162P11;CHEMBL1479411;DTXSID10451903;cid_11012459;BDBM114012;HMS3324N06;2-[alpha-(4-Chloroanilino)benzyl]cyclohexanone;2-[(4-chloroanilino)-phenyl-methyl]cyclohexanone;AQ-344/10508050;2-[(4-chloroanilino)-phenylmethyl]-1-cyclohexanone;2-[(phenyl)(4-chlorophenylamino)methyl]cyclohexanone;2-[[(4-chlorophenyl)amino]-phenyl-methyl]cyclohexan-1-one

Suppliers and Price of 2-[(4-Chloroanilino)(phenyl)methyl]cyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-[(4-Chloroanilino)(phenyl)methyl]cyclohexanone

Chemical Property:

PSA：29.10000
LogP:5.32550
XLogP3:4.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:313.1233420
Heavy Atom Count:22
Complexity:358

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(=O)C(C1)C(C2=CC=CC=C2)NC3=CC=C(C=C3)Cl

Technology Process of 2-[(4-Chloroanilino)(phenyl)methyl]cyclohexanone

There total 4 articles about 2-[(4-Chloroanilino)(phenyl)methyl]cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 100-52-7
benzaldehyde

: 106-47-8
4-chloro-aniline

: 21854-73-9
2-[1'-(N-p-chlorophenylamino)-1'-phenyl]methylcyclohexanone

Guidance literature:: dodecylbenzene-sulphonic acid; In water; at 23 ℃; for 1h;
DOI:10.1021/ol991113u

Reference yield: 90.0%

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 1613-89-4
(E)-N-benzylidene-4-chloroaniline

: 21854-73-9
2-[1'-(N-p-chlorophenylamino)-1'-phenyl]methylcyclohexanone

Guidance literature:: With hydrogenchloride; sodium dodecyl-sulfate; at 20 ℃;
DOI:10.1055/s-2004-836062

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 100-52-7
benzaldehyde

: 106-47-8
4-chloro-aniline

: 21854-73-9
C₁₉H₂₀ClNO

: 21854-73-9
C₁₉H₂₀ClNO

Guidance literature:: With Nafion-Н; In ethanol; at 20 ℃; for 4h; Overall yield = 95 %; diastereoselective reaction; Inert atmosphere; Green chemistry;
DOI:10.1134/S0023158412060079