2-[(4-bromoanilino)(phenyl)methyl]cyclohexanone

Base Information

Chemical Name:2-[(4-bromoanilino)(phenyl)methyl]cyclohexanone
CAS No.:21854-74-0
Molecular Formula:C19H20BrNO
Molecular Weight:358.278
Hs Code.:
Mol file:21854-74-0.mol

Synonyms:α-[α-(p-Bromanilino)benzyl]cyclohexanon;α-<α-(p-Bromanilino)benzyl>cyclohexanon;2-[(4-Bromo-phenylamino)-phenyl-methyl]-cyclohexanone;

Suppliers and Price of 2-[(4-bromoanilino)(phenyl)methyl]cyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[(4-bromoanilino)(phenyl)methyl]cyclohexanone

Chemical Property:

Melting Point:97 - 98 °C
PSA：29.10000
LogP:5.43460

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2-[(4-bromoanilino)(phenyl)methyl]cyclohexanone

There total 2 articles about 2-[(4-bromoanilino)(phenyl)methyl]cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 100-52-7
benzaldehyde

: 106-40-1
4-bromo-aniline

: 21854-74-0
2-((4-bromophenylamino)(phenyl)methyl)cyclohexanone

Guidance literature:: With zinc trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1016/j.tet.2006.08.063

Reference yield:

: 21854-74-0
2-((4-bromophenylamino)(phenyl)methyl)cyclohexanone

Guidance literature:: a) aus <11a> mit 47percentig. HBr (als Hauptprodukt neben <18b>);

Reference yield: 61.0%

: 21854-74-0
2-((4-bromophenylamino)(phenyl)methyl)cyclohexanone

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 5-(4-bromophenyl)-6-phenyl-5,6,7,8,9,10-hexahydrophenanthridine

Guidance literature:: 2-((4-bromophenylamino)(phenyl)methyl)cyclohexanone; 2-(trimethylsilyl)phenyl trifluoromethanesulfonate; With potassium fluoride; 18-crown-6 ether; In acetonitrile; at 20 ℃; Inert atmosphere;

With hydrogenchloride; In water; acetonitrile; for 1h; Inert atmosphere; Reflux;
DOI:10.1016/j.tet.2020.131372