3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole

Base Information

Chemical Name:3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole
CAS No.:219508-27-7
Molecular Formula:C8H5F3N4
Molecular Weight:214.15
Hs Code.:
Mol file:219508-27-7.mol

Synonyms:3-(trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole;3-(trifluoromethyl)-5-(2-pyridyl)triazole;(2-(5-trifluoromethyl)-2H-1,2,4-triazol-3-yl)-pyridine;2-(3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl)pyridine;Pyridine,2-[5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl];5-(pyridine-2'-yl)-3-trifluoromethyl-1,2,4-triazole;

Suppliers and Price of 3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine
5mg
$ 60.00

TCI Chemical
2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine >98.0%(GC)(T)
200mg
$ 68.00

TCI Chemical
2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine >98.0%(GC)(T)
1g
$ 232.00

AK Scientific
2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine
200mg
$ 145.00

Total 19 raw suppliers

Chemical Property of 3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole

Chemical Property:

Melting Point:157.0 to 161.0 °C
PSA：54.46000
LogP:1.88550

Purity/Quality:

97% ^*data from raw suppliers

2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole

There total 8 articles about 3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 100-70-9,1232006-36-8
2-Cyanopyridine

: 383-63-1
ethyl trifluoroacetate,

: 219508-27-7
1-pyridyl-3-trifluoromethyl-2,4,5-triazole

Guidance literature:: 2-Cyanopyridine; With sodium methylate; In ethanol; at 20 ℃; for 10h; Inert atmosphere;

With ammonium chloride; In ethanol; at 20 ℃; for 24h; Reflux;

ethyl trifluoroacetate,; Further stages;

Reference yield: 52.0%

: 100-70-9,1232006-36-8
2-Cyanopyridine

: 1538-08-5
2,2,2-trifluoroacetohydrazide

: 219508-27-7
5-trifluoromethyl-3-(2′-pyridyl)-2H-1,2,4-triazole

Guidance literature:: 2-Cyanopyridine; 2,2,2-trifluoroacetohydrazide; In ethanol; at 20 ℃; for 0.5h;

With sodium methylate; In methanol; ethanol; at 130 ℃; for 14h; Reflux;
DOI:10.1021/jo4012514