2-Propenoic acid, 3-(dimethylamino)-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2Z)-

Base Information

Chemical Name:2-Propenoic acid, 3-(dimethylamino)-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2Z)-
CAS No.:219739-90-9
Molecular Formula:C14H18N2O4
Molecular Weight:278.308
Hs Code.:
DSSTox Substance ID:DTXSID101140008
Nikkaji Number:J1.614.012K
Mol file:219739-90-9.mol

Synonyms:SCHEMBL10267296;DTXSID101140008;(Z)-2-(Benzyloxycarbonylamino)-3-(dimethylamino)acrylic acid methyl ester;Methyl (2Z)-3-(dimethylamino)-2-[[(phenylmethoxy)carbonyl]amino]-2-propenoate;219739-90-9

Suppliers and Price of 2-Propenoic acid, 3-(dimethylamino)-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2Z)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Propenoic acid, 3-(dimethylamino)-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2Z)-

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:278.12665706
Heavy Atom Count:20
Complexity:360

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C=C(C(=O)OC)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CN(C)/C=C(/C(=O)OC)\NC(=O)OCC1=CC=CC=C1

Technology Process of 2-Propenoic acid, 3-(dimethylamino)-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2Z)-

There total 3 articles about 2-Propenoic acid, 3-(dimethylamino)-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5815-08-7
tert-Butoxybis(dimethylamino)methane

: 1212-53-9
methyl N-benzyloxycarbonylglycinate

: 219739-90-9
Methyl (Z)-2-<(benzyloxycarbonyl)amino>-3-dimethylaminopropenoate

Guidance literature:: DOI:10.3987/COM-12-12432

Reference yield:

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

: 219739-90-9
Methyl (Z)-2-<(benzyloxycarbonyl)amino>-3-dimethylaminopropenoate

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / thionyl chloride / 2 h / 0 °C

2: 96 percent / toluene / 1 h / 100 °C

With thionyl chloride; In toluene;
DOI:10.1002/jhet.5570360135