4-Benzyloxy-3,5-dimethylbenzoyl chloride

Base Information

Chemical Name:4-Benzyloxy-3,5-dimethylbenzoyl chloride
CAS No.:219937-14-1
Molecular Formula:C16H15ClO2
Molecular Weight:274.747
Hs Code.:
DSSTox Substance ID:DTXSID20593101

Synonyms:4-benzyloxy-3,5-dimethylbenzoyl chloride;219937-14-1;SCHEMBL348412;DTXSID20593101;HGKOOLWZWVGOGC-UHFFFAOYSA-N;4-(benzyloxy)-3,5-dimethylbenzoyl chloride;DB-340049

Suppliers and Price of 4-Benzyloxy-3,5-dimethylbenzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Benzyloxy-3,5-dimethylbenzoyl chloride

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:274.0760574
Heavy Atom Count:19
Complexity:287

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1OCC2=CC=CC=C2)C)C(=O)Cl

Technology Process of 4-Benzyloxy-3,5-dimethylbenzoyl chloride

There total 5 articles about 4-Benzyloxy-3,5-dimethylbenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 97888-80-7
3,5-dimethyl-4-benzyloxy-benzoic acid

: 219937-14-1
4-benzyloxy-3,5-dimethylbenzoyl chloride

Guidance literature:: With thionyl chloride; In chloroform; for 2h; Heating / reflux;

Reference yield:

: 79-37-8
oxalyl dichloride

: 97888-80-7
3,5-dimethyl-4-benzyloxy-benzoic acid

: 219937-14-1
4-benzyloxy-3,5-dimethylbenzoyl chloride

Guidance literature:: In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 100-44-7
benzyl chloride

: 219937-14-1
4-benzyloxy-3,5-dimethylbenzoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1 h / Reflux

2: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 3 h / 20 °C

With oxalyl dichloride; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.joc.1c03160