1-Benzyl-4-butylpiperidin-4-ol

Base Information

Chemical Name:1-Benzyl-4-butylpiperidin-4-ol
CAS No.:22093-36-3
Molecular Formula:C16H25NO
Molecular Weight:247.381
Hs Code.:2933399090
Mol file:22093-36-3.mol

Synonyms:1-Benzyl-4-hydroxy-4-butylpiperidine;1-Benzyl-4-butyl-4-piperidinol;1-benzyl-4-butyl-piperidin-4-ol;1-Benzyl-4-butylpiperidinol;

Suppliers and Price of 1-Benzyl-4-butylpiperidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Benzyl-4-butylpiperidin-4-ol

Chemical Property:

PSA：23.47000
LogP:3.14160

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Benzyl-4-butylpiperidin-4-ol

There total 5 articles about 1-Benzyl-4-butylpiperidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 109-72-8,29786-93-4
n-butyllithium

: 3612-20-2
1-phenylmethyl-4-piperidone

: 2-[2-(2-bromophenyl)vinyl]-1,3-dioxolane

: 22093-36-3
1-Benzyl-4-hydroxy-4-butylpiperidine

: 1264244-36-1
2-(N-benzyl-3H-spiro[[2]-benzoxepine-1,4'-piperidin]-3-yloxyl)ethanol

Guidance literature:: n-butyllithium; 2-[2-(2-bromophenyl)vinyl]-1,3-dioxolane; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h; Inert atmosphere;

1-phenylmethyl-4-piperidone; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 18h; Inert atmosphere;

With water; In tetrahydrofuran; hexane; Inert atmosphere;
DOI:10.1016/j.bmc.2010.11.013

Reference yield: 55.0%

: 109-72-8,29786-93-4
n-butyllithium

: 3612-20-2
1-phenylmethyl-4-piperidone

: 22093-36-3
1-Benzyl-4-hydroxy-4-butylpiperidine

Guidance literature:: n-butyllithium; 1-phenylmethyl-4-piperidone; In diethyl ether; hexane; at 0 - 20 ℃;

With water; In diethyl ether; hexane;

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 693-04-9
butyl magnesium bromide

: 88-65-3
2-bromobenzoic-acid

: 22093-36-3
1-Benzyl-4-hydroxy-4-butylpiperidine

: 65-85-0,8013-63-6
benzoic acid

: 37663-42-6
1'-benzylspiro[isobenzofuran-1(3H),4'-piperidine]-3-one

Guidance literature:: butyl magnesium bromide; 2-bromobenzoic-acid; With n-butyllithium;

1-phenylmethyl-4-piperidone; Reagent/catalyst; Concentration;
DOI:10.1021/op0600963