(4R)-2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-4-carboxylic acid

Base Information

Chemical Name:(4R)-2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-4-carboxylic acid
CAS No.:222404-26-4
Molecular Formula:C12H16N2O2S
Molecular Weight:252.337
Hs Code.:
DSSTox Substance ID:DTXSID901176677
Mol file:222404-26-4.mol

Synonyms:(4R)-2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-4-carboxylic acid;222404-26-4;SCHEMBL8870735;DTXSID901176677;STK032247;AKOS010386876;NS-03778;CS-0300239;EN300-302498;(R)-2-(4-Dimethylamino-phenyl)-thiazolidine-4-carboxylic acid;(4r)-2-(4-(Dimethylamino)phenyl)thiazolidine-4-carboxylic acid;(4R)-2-[4-(Dimethylamino)phenyl]-4-thiazolidinecarboxylic acid

Suppliers and Price of (4R)-2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (4R)-2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-4-carboxylic acid

Chemical Property:

XLogP3:-0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:252.09324893
Heavy Atom Count:17
Complexity:278

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)C2NC(CS2)C(=O)O
Isomeric SMILES:CN(C)C1=CC=C(C=C1)C2N[C@@H](CS2)C(=O)O

Technology Process of (4R)-2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-4-carboxylic acid

There total 1 articles about (4R)-2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 52-90-4
L-Cysteine

: 100-10-7
4-dimethylamino-benzaldehyde

: 222404-26-4
(2RS,4R)-2-(4-dimethyloamino-phenyl)-thiazolidine-4-carboxylic acid

Guidance literature:: In ethanol; at 20 ℃; for 5h;
DOI:10.1021/jm049208b

Reference yield: 90.0%

: 222404-26-4
(2RS,4R)-2-(4-dimethyloamino-phenyl)-thiazolidine-4-carboxylic acid

: 76740-20-0
(D)-3-(benzoylthio)-2-methylpropanoic acid chloride

: 72679-37-9
(R)-3-((S)-3-Benzoylsulfanyl-2-methyl-propionyl)-2-(4-dimethylamino-phenyl)-thiazolidine-4-carboxylic acid

Guidance literature:: With sodium hydrogencarbonate; In water; for 1h;
DOI:10.1248/cpb.30.440

Reference yield: 75.0%

: 222404-26-4
(2RS,4R)-2-(4-dimethyloamino-phenyl)-thiazolidine-4-carboxylic acid

: 124-30-1
1-aminooctadecane

: (2RS,4R)-2-(4-dimethylaminophenyl)-thiazolidine-4-carboxylic acid octadecylamide

Guidance literature:: (2RS,4R)-2-(4-dimethyloamino-phenyl)-thiazolidine-4-carboxylic acid; With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; for 0.166667h;

1-aminooctadecane; In dichloromethane; at 20 ℃;
DOI:10.1021/jm049208b