allyl N-(2-aminoethyl)carbamate

Base Information

• Chemical Name: allyl N-(2-aminoethyl)carbamate
• CAS No.: 223741-66-0
• Molecular Formula: C6H12N2O2
• Molecular Weight: 144.17200
• DSSTox Substance ID: DTXSID40584096
• Nikkaji Number: J1.822.077F
• Wikidata: Q82475727
• Mol file: 223741-66-0.mol

Synonyms:allyl N-(2-aminoethyl)carbamate;223741-66-0;Allyl (2-aminoethyl)carbamate;prop-2-enyl N-(2-aminoethyl)carbamate;Carbamic acid, N-(2-aminoethyl)-, 2-propen-1-yl ester;N-Alloc-ethylenediamine hydrochloride;Allyl 2-aminoethylcarbamate;Allyl(2-aminoethyl)carbamate;SCHEMBL7001155;DTXSID40584096;ZRB72241;MFCD08062281;AKOS006283729;BS-28114;Prop-2-en-1-yl (2-aminoethyl)carbamate;HY-145735;H11912

Chemical Property of allyl N-(2-aminoethyl)carbamate

Chemical Property:

• Vapor Pressure: 0.0241mmHg at 25°C
• Boiling Point: 248.6oC at 760 mmHg
• Flash Point: 104.1oC
• PSA: 67.84000
• Density: 1.039g/cm3
• LogP: 0.76200
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 144.089877630
• Heavy Atom Count: 10
• Complexity: 114

Purity/Quality:

97% ^*data from raw suppliers

Allyl(2-aminoethyl)carbamate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCOC(=O)NCCN

Technology Process of allyl N-(2-aminoethyl)carbamate

There total 7 articles about allyl N-(2-aminoethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-(allyloxycarbonyl)-4-(tert-butyloxycarbonyl)ethyldiamine (438012-35-2) → 1-N-(allyloxycarbonyl)-1,2-diaminoethane (223741-66-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1039/c6cc00624h

Reference yield: 97.0%

allyl 1-benzotriazolyl carbonate (102423-16-5) + ethylenediamine (107-15-3,85404-18-8) → 1-N-(allyloxycarbonyl)-1,2-diaminoethane (223741-66-0)

Guidance literature:

In dichloromethane; at 20 ℃; for 19h; Inert atmosphere;

DOI:10.1002/chem.201302972

Reference yield: 67.0%

allyl phenyl carbonate (16308-68-2) + ethylenediamine (107-15-3,85404-18-8) → 1-N-(allyloxycarbonyl)-1,2-diaminoethane (223741-66-0)

Guidance literature:

In ethanol; at 20 ℃;

DOI:10.1055/s-2002-34859

upstream raw materials:

diallylcarbonate

ethylenediamine

allyl phenyl carbonate

2-bromo-6-methylphenol

Downstream raw materials:

2'-amino-3'-O-(tert-butyldimethylsilyl)-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N₄-(allyloxycarbonylaminoethyl)cytidine

2'-(anthraquinone-2-ylcarboxamido)-3'-O-(tert-butyldimethylsilyl)-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N₄-(allyloxycarbonylaminoethyl)cytidine