Tert-butyl diphenyl phosphate

Base Information

• Chemical Name: Tert-butyl diphenyl phosphate
• CAS No.: 22433-83-6
• Molecular Formula: C16H19O4P
• Molecular Weight: 306.298
• Hs Code.: 2919900090
• DSSTox Substance ID: DTXSID60276047
• Nikkaji Number: J1.734.395E
• Wikidata: Q82006364
• Mol file: 22433-83-6.mol

Synonyms:tert-butyl diphenyl phosphate;22433-83-6;Phosphoric acid, 1,1-dimethylethyl diphenyl ester;SCHEMBL464914;t-butyl phenyl phenyl phosphate;DTXSID60276047

Chemical Property of Tert-butyl diphenyl phosphate

Chemical Property:

• PSA: 54.57000
• LogP: 5.06760
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 306.10209608
• Heavy Atom Count: 21
• Complexity: 328

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)OP(=O)(OC1=CC=CC=C1)OC2=CC=CC=C2

Technology Process of Tert-butyl diphenyl phosphate

There total 5 articles about Tert-butyl diphenyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96%

chlorophosphoric acid diphenyl ester (2524-64-3) + tert-butyl alcohol (75-65-0) → (2-methyl-2-propyl) diphenyl phosphate (22433-83-6)

Guidance literature:

With molybdenum(VI) tetrachloride oxide; triethylamine; In dichloromethane; at 20 ℃; for 30h;

DOI:10.1002/adsc.200900279

Reference yield: 61%

tert-butyl alcohol (75-65-0) + (2-oxo-5,5-diphenyl-oxazolidin-3-yl)-phosphonic acid diphenyl ester (681035-22-3) → (2-methyl-2-propyl) diphenyl phosphate (22433-83-6)

Guidance literature:

With N,N'-bis(benzyliden)ethylendiamine; copper(II) bis(trifluoromethanesulfonate); triethylamine; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1021/ol051104n

Reference yield: 23%

3-(diphenylphosphono)-2-(N-cyanoimino)thiazolidine (449813-82-5) + tert-butyl alcohol (75-65-0) → (2-methyl-2-propyl) diphenyl phosphate (22433-83-6)

Guidance literature:

With tert-butylmagnesium chloride; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1016/S0040-4020(02)00312-5

upstream raw materials:

diphenyl (4,6-dimethyl-2-pyrimidyl) phosphate

tert-butyl alcohol

3-(diphenylphosphono)-2-(N-cyanoimino)thiazolidine

(2-oxo-5,5-diphenyl-oxazolidin-3-yl)-phosphonic acid diphenyl ester

Refernces

• 1、 Xue, Weihua,Zhang, Lifen. "B(C6F5)3 as a highly effective catalyst for the phosphoryl transfer reaction". . p. 1797 - 1800. Retrieved 2012/10/29.
• 2、 Jones, Simon,Smanmoo, Chaiwat. "Phosphorylation of alcohols with N-phosphoryl oxazolidinones employing copper(II) triflate catalysis". . p. 3271 - 3274. Retrieved 2007/10/03.