Butylidenecyclohexane

Base Information

• Chemical Name: Butylidenecyclohexane
• CAS No.: 2272-03-9
• Molecular Formula: C10H18
• Molecular Weight: 138.253
• Hs Code.: 2902199090
• Mol file: 2272-03-9.mol

Synonyms:Butylidencyclohexanon;Cyclohexane,butylidene;Butyliden-cyclohexan;n-Butyliden-cyclohexan;

Chemical Property of Butylidenecyclohexane

Chemical Property:

• PSA: 0.00000
• LogP: 3.67700

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Butylidenecyclohexane

There total 7 articles about Butylidenecyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-vinylcyclohexene (2622-21-1) + ethyllithium (811-49-4) → cyclohexane, butylidene (2272-03-9)

Guidance literature:

With hydrogenchloride; zirconocene dichloride;

DOI:10.1021/jo00306a022

Reference yield: 55.0%

n-butyl(triphenyl)phosphonium bromide (1779-51-7) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → cyclohexane, butylidene (2272-03-9)

Guidance literature:

With potassium tert-butylate; In benzene; 1.) 0 deg C - 4 deg C, 2 h, 2.) r.t., 72 h;

Reference yield:

1-vinylcyclohexene (2622-21-1) + ethyllithium (811-49-4) → cyclohexane, butylidene (2272-03-9)

Guidance literature:

Yield given. Multistep reaction; 1.) Et₂O, THF, -78 deg C, 1 h, 2.) Et₂O, THF, from -78 deg C to 25 deg C;

DOI:10.1021/jo00287a008

upstream raw materials:

ethyllithium

cyclohexanone

vinyltriphenylphosphonium bromide

Cyclohexylphosphonsaeurebis(dimethylamid)

Downstream raw materials:

1-(1-bromobutyl)cyclohexanol

Refernces

• 1、 Negishi, Ei-ichi,Swanson, Douglas R.,Rousset, Christophe J.. "Clean and Convenient Procedure for Converting Primary Alkyl Iodides and α,ω-Diiodoalkanes into the Corresponding Alkyllithium Derivatives by Treatment with tert-Butyllithium". . p. 5406 - 5409. Retrieved 2007/10/02.
• 2、 Dehmlow, Eckehard V.,Barahona-Naranjo, Simon. "Anwendungen der Phasentransfer-Katalyse 17. Wittig-Reaktionen in verschiedenen Zweiphasen-Systemen". . p. 1748 - 1762. Retrieved 2007/10/02.