ISOVALERYLUREA

Base Information

• Chemical Name: ISOVALERYLUREA
• CAS No.: 2274-08-0
• Molecular Formula: C6H12N2O2
• Molecular Weight: 144.17200
• Hs Code.: 2924210090
• Mol file: 2274-08-0.mol

Synonyms:Monoisovaleryl-harnstoff;Isovaleryl-harnstoff;<3-Methyl-butyryl>-harnstoff;Isovaleriansaeure-ureid;ISOVALERYLUREA;

Chemical Property of ISOVALERYLUREA

Chemical Property:

• PSA: 76.67000
• LogP: 1.58150

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ISOVALERYLUREA

There total 4 articles about ISOVALERYLUREA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

bromisoval (496-67-3) → N-carbamoyl-3-methylbutanamide (2274-08-0)

Guidance literature:

With water; zinc; In acetonitrile; at 80 ℃; for 7h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.joc.9b02026

Reference yield: 71.0%

urea (57-13-6) + isopentanoyl chloride (108-12-3) → N-carbamoyl-3-methylbutanamide (2274-08-0)

Guidance literature:

In acetonitrile; for 2h;

Reference yield: 39.0%

C12H14O2S → N-carbamoyl-3-methylbutanamide (2274-08-0)

Guidance literature:

With trimethylsilylazide; copper diacetate; In N,N-dimethyl-formamide; at 80 ℃; for 1h; Molecular sieve; Inert atmosphere;

DOI:10.1021/acs.joc.7b03054

upstream raw materials:

urea

isopentanoyl chloride

bromisoval