n,n-Bis(trimethylsilyl)-2,3,4,5,6-pentafluoroaniline

Base Information

• Chemical Name: n,n-Bis(trimethylsilyl)-2,3,4,5,6-pentafluoroaniline
• CAS No.: 23188-59-2
• Molecular Formula: C₁₂H₁₈F₅NSi₂
• Molecular Weight: 327.445
• European Community (EC) Number: 659-768-6
• Nikkaji Number: J2.142.252E
• Mol file: 23188-59-2.mol

Synonyms:23188-59-2;n,n-bis(trimethylsilyl)-2,3,4,5,6-pentafluoroaniline;AKOS024338590;N-(2,3,4,5,6-pentafluorophenyl)-N,N-bis(trimethylsilyl)amine

Chemical Property of n,n-Bis(trimethylsilyl)-2,3,4,5,6-pentafluoroaniline

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 327.08979346
• Heavy Atom Count: 20
• Complexity: 314

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)N(C1=C(C(=C(C(=C1F)F)F)F)F)[Si](C)(C)C

Technology Process of n,n-Bis(trimethylsilyl)-2,3,4,5,6-pentafluoroaniline

There total 4 articles about n,n-Bis(trimethylsilyl)-2,3,4,5,6-pentafluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,5,6-pentafluoroaniline (771-60-8) → (pentafluorophenyl)N(SiMe3)2 (23188-59-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran

In tetrahydrofuran;

Reference yield:

chloro-trimethyl-silane (75-77-4) + lithium perfluorophenylimide → (pentafluorophenyl)N(SiMe3)2 (23188-59-2)

Guidance literature:

DOI:10.1016/S0022-328X(00)80223-5

Reference yield:

chloro-trimethyl-silane (75-77-4) + 2,3,4,5,6-pentafluoroaniline (771-60-8) → (pentafluorophenyl)N(SiMe3)2 (23188-59-2)

Guidance literature:

Multistep reaction; (i) nBuLi, THF, (ii) /BRN= 1209232/;

DOI:10.1016/S0022-328X(00)80223-5

upstream raw materials:

chloro-trimethyl-silane

2,3,4,5,6-pentafluoroaniline

Downstream raw materials:

[Ti(N-pentafluorophenyl)Cl(μ-Cl)(THF)2]2