(R)-1-Methoxypropan-2-yl 4-methylbenzenesulfonate

Base Information

• Chemical Name: (R)-1-Methoxypropan-2-yl 4-methylbenzenesulfonate
• CAS No.: 23946-74-9
• Molecular Formula: C11H16O4S
• Molecular Weight: 244.312
• European Community (EC) Number: 806-566-2
• Nikkaji Number: J811.322J
• Mol file: 23946-74-9.mol

Synonyms:1-methoxypropan-2-yl 4-methylbenzenesulfonate;(R)-1-Methoxypropan-2-yl 4-methylbenzenesulfonate;114114-89-5;23946-74-9;SCHEMBL320440;QPPFIRCWDRIUEZ-UHFFFAOYSA-N;EN300-77181;1-methoxypropan-2-yl 4-methylbenzene-1-sulfonate;p-toluenesulphonic acid-(1-methoxyprop-2-yl)-ester;(+/-)-2-Methoxy-1-methylethyl 4-methylbenzenesulfonate;toluene-4-sulphonic acid 2-methoxy-1-methyl-ethyl ester;Toluene-4-sulphonic Acid 2-methoxy-1-methylethyl Ester

Chemical Property of (R)-1-Methoxypropan-2-yl 4-methylbenzenesulfonate

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 244.07693016
• Heavy Atom Count: 16
• Complexity: 286

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC(C)COC

Technology Process of (R)-1-Methoxypropan-2-yl 4-methylbenzenesulfonate

There total 2 articles about (R)-1-Methoxypropan-2-yl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1-methoxy-2-propanol (107-98-2) + p-toluenesulfonyl chloride (98-59-9) → 1-methoxypropan-2-yl 4-methylbenzenesulfonate (23946-74-9)

Guidance literature:

In dichloromethane;

Reference yield:

→ 1-methoxypropan-2-yl 4-methylbenzenesulfonate (23946-74-9)

Guidance literature:

aus p-Toluolsulfonylchlorid, 1-Methoxy-2-propanol;

Reference yield:

1-methoxypropan-2-yl 4-methylbenzenesulfonate (23946-74-9) + phenylmagnesium bromide (100-58-3) → 2-phenyl-1-propyl methyl ether (65738-46-7) + (1-methoxypropyl)benzene (59588-12-4)

Guidance literature:

phenylmagnesium bromide; With ZnI₂(tmeda); In tetrahydrofuran;

1-methoxypropan-2-yl 4-methylbenzenesulfonate; With iron(III) chloride; In tetrahydrofuran; at 0 - 40 ℃;

DOI:10.1021/ol901610a

upstream raw materials:

1-methoxy-2-propanol

p-toluenesulfonyl chloride

Downstream raw materials:

2-Chloro-N-(2-ethoxy-1-methyl-ethyl)-N-(2-fluoro-phenyl)-acetamide

2-Chloro-N-(2-ethyl-6-methoxy-phenyl)-N-(2-methoxy-1-methyl-ethyl)-acetamide

(2,3-Dimethyl-phenyl)-(2-methoxy-1-methyl-ethyl)-amine

(2-Chloro-6-methyl-phenyl)-(2-methoxy-1-methyl-ethyl)-amine