2,2-Diphenylcyclobutan-1-one

Base Information

• Chemical Name: 2,2-Diphenylcyclobutan-1-one
• CAS No.: 24104-20-9
• Molecular Formula: C16H14O
• Molecular Weight: 222.287
• DSSTox Substance ID: DTXSID20496325
• Nikkaji Number: J1.652.898F
• Wikidata: Q82345101
• Mol file: 24104-20-9.mol

Synonyms:2,2-Diphenylcyclobutan-1-one;2,2-diphenylcyclobutanone;24104-20-9;2,2-Diphenyl-cyclobutanone;2,2-diphenyl-cyclobutan-1-one;SCHEMBL11489569;DTXSID20496325

Chemical Property of 2,2-Diphenylcyclobutan-1-one

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 222.104465066
• Heavy Atom Count: 17
• Complexity: 264

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 2,2-Diphenylcyclobutan-1-one

There total 14 articles about 2,2-Diphenylcyclobutan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diphenylmethylenecyclopropene (7632-57-7) → 2,2-diphenylcyclobutanone (24104-20-9)

Guidance literature:

With di-isopropyl azodicarboxylate; zirconium triflate; In acetonitrile; at 20 ℃; for 48h;

DOI:10.1002/ejoc.200300515

Reference yield: 50.0%

diphenylmethylenecyclopropene (7632-57-7) → 2,2-diphenylcyclobutanone (24104-20-9) + 2,4-dichloro-1,1-diphenylbut-1-ene

Guidance literature:

With titanium tetrachloride; diethylazodicarboxylate; In diethyl ether; at 20 ℃; for 8h;

DOI:10.1002/ejoc.200400388

Reference yield: 31.0%

diphenylmethylenecyclopropene (7632-57-7) → benzophenone (119-61-9) + 2,2-diphenylcyclobutanone (24104-20-9)

Guidance literature:

With dihydrogen peroxide; In acetonitrile; at 50 ℃; for 24h;

DOI:10.1002/cctc.201501309

upstream raw materials:

benzophenone

cyclopropyldiphenylsulfonium tetrafluoroborate

diphenylmethylenecyclopropene

ethene

Downstream raw materials:

methyl 4,4-diphenylbutanoate

2,2-diphenyl-1-(N-methoxy-N-methylcarbonylmethyl)cyclobutane

2,2-diphenylcyclobutylcarbinyl radical

(2,2-diphenylcyclobutyl)acetic acid