9H-fluorene-9-carbonyl chloride

Base Information

• Chemical Name: 9H-fluorene-9-carbonyl chloride
• CAS No.: 24168-51-2
• Molecular Formula: C14H9ClO
• Molecular Weight: 228.678
• DSSTox Substance ID: DTXSID90364921
• Nikkaji Number: J1.934.663C
• Wikidata: Q82149147
• Mol file: 24168-51-2.mol

Synonyms:9H-fluorene-9-carbonyl chloride;24168-51-2;9H-Fluorene-9-carbonylchloride;SCHEMBL1215825;DTXSID90364921;9H-fluorene-9-carbonyl chloride, AldrichCPR;AR-360/40448612

Chemical Property of 9H-fluorene-9-carbonyl chloride

Chemical Property:

• Melting Point: 74-75 °C
• Boiling Point: 362.0±31.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.310±0.06 g/cm3(Predicted)
• LogP: 3.56430
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 228.0341926
• Heavy Atom Count: 16
• Complexity: 267

Purity/Quality:

95% ^*data from raw suppliers

9H-FLUORENE-9-CARBONYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)C(=O)Cl

Technology Process of 9H-fluorene-9-carbonyl chloride

There total 7 articles about 9H-fluorene-9-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

2-chloro-2,2-diphenylacetyl chloride (2902-98-9) → 9H-fluorene-9-carbonyl chloride (24168-51-2) + 2,2-dichloro-1,2-diphenylethanone (31315-51-2)

Guidance literature:

iron(III) chloride; In benzene; for 1h; Heating;

Reference yield:

9H-fluorene-9-carboxylic acid (1989-33-9) → 9H-fluorene-9-carbonyl chloride (24168-51-2)

Guidance literature:

With tetrachloromethane; thionyl chloride;

Reference yield:

Benzilic acid (76-93-7) → 9H-fluorene-9-carbonyl chloride (24168-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / 0.75 h / Heating

2: 30 percent / FeCl₃ / benzene / 1 h / Heating

With thionyl chloride; iron(III) chloride; In benzene;

upstream raw materials:

9H-fluorene-9-carboxylic acid

2-chloro-2,2-diphenylacetyl chloride

Benzilic acid

phenylglyoxylic acid ethyl ester

Downstream raw materials:

9-(4-Methylpiperazinocarbonyl)fluoren

fluorene-9-carboxylic acid-(1-methyl-[4]piperidylester); hydrochloride

fluorene-9-carboxylic acid-(1,2,6-trimethyl-[4]piperidylester); hydrochloride

9H-fluorene-9-carboxamide